Evidence map›Paper›PMID 30138478›Full record

ArticlePloS one2018

Multidisciplinary predialysis education reduces incidence of peritonitis and subsequent death in peritoneal dialysis patients: 5-year cohort study.

Cheng-Kai Hsu, Chin-Chan Lee, Yih-Ting Chen, Ming-Kuo Ting, Chiao-Yin Sun, Chun-Yu Chen, Heng-Jung Hsu, Yung-Chang Chen, I-Wen Wu

Abstract readComparative Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng-Kai HsuDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.ORCID 0000-0002-6812-526X
Chin-Chan LeeDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Yih-Ting ChenDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Ming-Kuo TingDivision of Endocrinology and Metabolism, Chang Gung Memorial Hospital, Keelung, Taiwan.
Chiao-Yin SunDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Chun-Yu ChenDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Heng-Jung HsuDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Yung-Chang ChenDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.
I-Wen WuDepartment of Nephrology, Chang Gung Memorial Hospital, Keelung, Taiwan.ORCID 0000-0001-8535-3582

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTechnique failure secondary to peritonitis is a grave impediment to remain in peritoneal dialysis (PD) therapy leading to high mortality. Multidisciplinary predialysis education (MPE) has shown improvement in outcomes of chronic kidney disease (CKD) patients. However, the legacy effects of MPE in PD patients remain unclear.

methodsAll patients who started PD at single hospital in 2007-16 were enrolled. The incidences of peritonitis and peritonitis-related mortality were compared between MPE recipients and non-recipients. The content of the MPE was standardized in accordance with the NKF/DOQI guidelines. Kaplan-Meier analysis and Cox proportional hazards model were applied to identify the prognostic factors associated with peritonitis-free survival.

resultsOf 398 PD patients, 169 patients had received MPE before starting PD. The patients of MPE group had a lower peritonitis rate [median (IQR) 0 (0.29) versus 0.11 (0.69) episodes/person-year, P< 0.001] and a lower percentage of peritonitis-related deaths (3.6% versus 8.7%, P = 0.04) compared with the non-MPE group. The median time to the first episode of peritonitis in the non-MPE and MPE groups was 33.9 months and 46.7 months, respectively (Cox-Mantel log rank test, P = 0.003). Cox regression analysis revealed that MPE assignment (HR: 0.594; 95% CI: 0.434-0.813, P< 0.001) were significant independent predictors for peritonitis-free survival.

conclusionsAn efficient standardized MPE program may prolong the time to the first episode of peritonitis and reduce peritonitis rate, independent of age, gender, diabetes, hypertension, educational status and PD modality. Subsequently, decreased peritonitis-related death.

Indexed as

AdultAgedCohort StudiesFemaleHumansIncidenceKaplan-Meier EstimateKidney Failure, ChronicMiddle AgedPatient Education as TopicPeritoneal DialysisPeritonitisProspective StudiesRetrospective StudiesRisk Factors

Identifiers

PMID30138478
PMCPMC6107258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.