Evidence map›Paper›PMID 30138066›Full record

ArticleAmerican journal of public health2018

Yield of Low-Dose Computerized Tomography Screening for Lung Cancer in High-Risk Workers: The Case of 7189 US Nuclear Weapons Workers.

Steven B Markowitz, Amy Manowitz, Jeffery A Miller, James S Frederick, Amaka C Onyekelu-Eze, Shannon A Widman, Lewis D Pepper, Albert Miller

Abstract read
In one paragraph

Article in American journal of public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Brazilian Thoracic Society recommendations for the diagnosis and monitoring of asbestos-exposed individuals.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024
    Guideline
  2. Article
  3. Article
  4. Review
  5. Lung Cancer Screening in Asbestos-Exposed Populations.International journal of environmental research and public health · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. La Medicina del lavoro · 2019
    Article
  10. La Medicina del lavoro · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Steven B MarkowitzSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Amy ManowitzSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Jeffery A MillerSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
James S FrederickSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Amaka C Onyekelu-EzeSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Shannon A WidmanSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Lewis D PepperSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.
Albert MillerSteven B. Markowitz, Amy Manowitz, Amaka C. Onyekelu-Eze, Lewis D. Pepper, and Albert Miller are with Barry Commoner Center for Health and the Environment, Queens College, City University of New York, Flushing, NY. Jeffrey A. Miller is with the Department of Veterans Affairs New Jersey Health Care System East Orange Campus, Department of Radiology, East Orange. James S. Frederick is with United Steelworkers, Health, Safety, and Environment Department, Pittsburgh, PA. Shannon A. Widman is with Duke Office of Clinical Research, Duke University School of Medicine, Durham, NC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the lung cancer screening yield and stages in a union-sponsored low-dose computerized tomography scan program for nuclear weapons workers with diverse ages, smoking histories, and occupations.

methodsWe implemented a low-dose computerized tomography program among 7189 nuclear weapons workers in 9 nonmetropolitan US communities during 2000 to 2013. Eligibility criteria included age, smoking, occupation, radiographic asbestos-related fibrosis, and a positive beryllium lymphocyte proliferation test.

resultsThe proportion with screen-detected lung cancer among smokers aged 50 years or older was 0.83% at baseline and 0.51% on annual scan. Of 80 lung cancers, 59% (n = 47) were stage I, and 10% (n = 8) were stage II. Screening yields of study subpopulations who met the National Lung Screening Trial or the National Comprehensive Cancer Network Group 2 eligibility criteria were similar to those found in the National Lung Screening Trial.

conclusionsComputerized tomography screening for lung cancer among high-risk workers leads to a favorable yield of early-stage lung cancers. Public Health Implications. Health equity and efficiency dictate that screening high-risk workers for lung cancer should be an important public health priority.

Indexed as

Mass ScreeningNuclear WeaponsRadiation ExposureTomography, X-Ray ComputedAgedFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasms, Radiation-InducedNeoplasm StagingOccupational DiseasesOccupational ExposureRadiation DosageRisk Factors

Identifiers

PMID30138066
PMCPMC6137787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.