ArticleThe Libyan journal of medicine2018
Protective effect of breastfeeding against childhood leukemia in Zhejiang Province, P. R. China: a retrospective case-control study.
Article in The Libyan journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Early Life Nutrition Factors and Risk of Acute Leukemia in Children: Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Role of breastfeeding on maternal and childhood cancers: An umbrella review of meta-analyses.Journal of global health · 2023Pooled it
- Comprehensive Modalities for Cataract Management: Preventive, Surgical, and Non-Surgical Approaches Using Conventional and Nanotechnology-Based Therapies.AAPS PharmSciTech · 2026Review
- Review
- A gut instinct for childhood leukemia prevention: microbiome-targeting recommendations aimed at parents and caregivers.Frontiers in public health · 2024Review
- Hair Dye Ingredients and Potential Health Risks from Exposure to Hair Dyeing.Chemical research in toxicology · 2022Review
- Association between maternal breastfeeding and risk of systemic neoplasms of offspring.Italian journal of pediatrics · 2022Review
- A systematic review and meta-analysis on the risk factors of acute myeloid leukemia.Translational cancer research · 2022Article
- Breastfeeding Experiences During the COVID-19 Lockdown in the United Kingdom: An Exploratory Study Into Maternal Opinions and Emotional States.Journal of human lactation : official journal of International Lactation Consultant Association · 2021Article
- miR-188-5p Promotes Tumor Growth by Targeting CD2AP Through PI3K/AKT/mTOR Signaling in Children with Acute Promyelocytic Leukemia.OncoTargets and therapy · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesOur research investigated the relationship between childhood leukemia and breastfeeding in the P. R. of China.
methodsWe conducted a retrospective case-control study from March 2008 to April 2017 at the Children's Hospital of Zhejiang University, Zhejiang province, P. R. of China, which reviewed 958 children who had been diagnosed with leukemia in case group and 785 healthy children in control group. Data were obtained from medical records, and if the medical records were incomplete, we called mothers of children by phone to complete the data.
resultsBreastfeeding reduces the risk of childhood leukemia; the effect is greater, if feeding continued for 7-9 months (p = 0.002). In addition, we suggest that some factors such as maternal age, smoking during pregnancy, abortion history, genetic factors, parents use of hair dye, and the history of using birth control pills before pregnancy can increase the risk of childhood leukemia.
conclusionsThis study indicates that promoting breastfeeding for 7-9 months may help lower the childhood leukemia incidence. Our study firstly demonstrates that breastfeeding has protective effects against childhood leukemia in the P. R. of China. ABBREVIATIONS: ALL: Acute lymphocytic leukemia; AML: Acute myeloid leukemia.
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Registered trials
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