Evidence map›Paper›PMID 30138013›Full record

Trial reportJournal of consulting and clinical psychology2018

Results from the Child/Adolescent Anxiety Multimodal Longitudinal Study (CAMELS): Functional outcomes.

Anna J Swan, Philip C Kendall, Thomas Olino, Golda Ginsburg, Courtney Keeton, Scott Compton, John Piacentini, Tara Peris, Dara Sakolsky, Boris Birmaher and 1 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Cognitive Functioning in Youth with Anxiety Disorders: A Systematic Review.Clinical child and family psychology review · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna J SwanDepartment of Child and Adolescent Psychiatry, Hassenfeld Children's Hospital at NYU Langone.ORCID 0000-0003-2793-560X
Philip C KendallDepartment of Psychology, Temple University.
Thomas OlinoDepartment of Psychology, Temple University.
Golda GinsburgChild Division of Department of Psychiatry, University of Connecticut Health.
Courtney KeetonDepartment of Psychiatry and Behavioral Services, Johns Hopkins University School of Medicine.
Scott ComptonDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center.
John PiacentiniDivision of Child and Adolescent Psychiatry, University of California, Los Angeles.
Tara PerisDivision of Child and Adolescent Psychiatry, University of California, Los Angeles.
Dara SakolskyDepartment of Psychiatry, University of Pittsburgh.
Boris BirmaherDepartment of Psychiatry, University of Pittsburgh.
Anne Marie AlbanoDepartment of Psychiatry, Columbia University.

Funding

Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN · 2002 to 2007
$3.1M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064003 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS · 2002 to 2007
$2.7M
Child and Adolescent Anxiety Multisite Study (CAMS)U01MH064107 · NIMH · DUKE UNIVERSITY · PI MARCH, JOHN S · 2002 to 2007
$2.4M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH063747 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2002 to 2007
$2.2M
Child/Adolescent Anxiety Multimodal Treatment StudyU01MH064088 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 2002 to 2007
$2.1M
5/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064107 · NIMH · DUKE UNIVERSITY · PI COMPTON, SCOTT N · 2010 to 2014
$1.3M
3/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064089 · NIMH · JOHNS HOPKINS UNIVERSITY · PI GINSBURG, GOLDA SUSAN, KEETON, COURTNEY PIERCE · 2010 to 2014
$925k
2/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064003 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SAKOLSKY, DARA JENNIFER · 2010 to 2014
$659k
4/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH063747 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI KENDALL, PHILIP C · 2010 to 2014
$618k
6/6-Child/Adolescent Anxiety Multimodal Extended Long-Term Study (CAMELS)R01MH064088 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI PIACENTINI, JOHN C. · 2010 to 2014
$611k
NIMH NIH HHS R01 MH063747NIMH NIH HHS R01 MH064003NIMH NIH HHS R01 MH064088NIMH NIH HHS R01 MH064089NIMH NIH HHS R01 MH064107NIMH NIH HHS U01 MH063747NIMH NIH HHS U01 MH064003NIMH NIH HHS U01 MH064088NIMH NIH HHS U01 MH064089NIMH NIH HHS U01 MH064107
6 · The paper itself

Abstract

objectiveTo report functional outcomes from the multisite Child/Adolescent Anxiety Multimodal Extended Long-term Study (CAMELS), which examined the impact of youth anxiety treatment (cognitive-behavioral therapy [CBT], coping cat; Sertraline, SRT; COMB [CBT + SRT]; pill placebo) on (a) global and (b) domain-specific functioning assessed an average of 3.1 times, 3- to 12-years postrandomization (first assessment = mean 6.5 years postrandomization).

methodThree-hundred and 19 of 488 families from the Child/Adolescent Anxiety Multimodal Study (CAMS; Walkup et al., 2008) participated. Growth curve modeling examined the impact of treatment condition and acute treatment outcomes (i.e., response, remission) on global functioning, global and domain-specific impairment, and life satisfaction across follow-up visits. Logistic regressions explored the impact of treatment remission and condition on low frequency events (arrests/convictions) and education.

resultsTreatment responders and remitters demonstrated better global functioning, decreased overall impairment, and increased life satisfaction at follow-up. Treatment remission, but not response, predicted decreased domain-specific impairment (social relationships, self-care/independence, academic functioning), and maintenance of increased life satisfaction across follow-ups. Participants in the CBT condition, compared with pill placebo, demonstrated improved trajectories pertaining to life satisfaction, overall impairment, and impairment in academic functioning. Randomization to CBT or COMB treatment was associated with increasing employment rates. Trajectories for participants randomized to SRT was not significantly different from placebo. Treatment outcome and condition did not predict legal outcomes, school/work variables, or family life.

conclusionPositive early intervention outcomes are associated with improved overall functioning, life satisfaction, and functioning within specific domains 6.5 years posttreatment. Treatment type differentially predicted trajectories of functioning. Findings support the positive impact of pediatric anxiety treatment into adolescence and early adulthood. (PsycINFO Database Record

Indexed as

AdolescentAnxiety DisordersChildCognitive Behavioral TherapyCombined Modality TherapyFemaleHumansLongitudinal StudiesMaleSelective Serotonin Reuptake InhibitorsSelf CareSertralineTreatment OutcomeYoung AdultSelective Serotonin Reuptake InhibitorsSertraline

Identifiers

PMID30138013
PMCPMC6110105

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.