ArticleInfluenza and other respiratory viruses2019
The impact of influenza infection on young children, their family and the health care system.
Article in Influenza and other respiratory viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
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Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Viral etiology of acute respiratory infections in Sub-Saharan Africa during the pre-COVID-19 period (2006-2019): a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024-25 Influenza Season.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2024Guideline
- Impact of Influenza and Influenza-Like Illness on Work Productivity Outcomes: A Systematic Literature Review.PharmacoEconomics · 2023Pooled it
- Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022-23 Influenza Season.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2022Guideline
- Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2019-20 Influenza Season.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2019Guideline
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- Adjuvants enhance protective antibodies against seasonal influenza viruses following a single vaccination of Fluzone.Virology · 2026Article
- The association of maternal and infant early gut microbiota with respiratory infections in infants.Pediatric research · 2026Article
- Phytotherapeutic, Homeopathic Interventions and Bee Products for Pediatric Infections: A Scoping Review.Nutrients · 2025Article
- Chronic Diseases and Influenza Vaccines.Vaccines · 2025Review
- Article
- Dynamics of Absences Due to Respiratory Infections, Including COVID-19, Among Medical Staff in a Regional Pediatric Hospital.Healthcare (Basel, Switzerland) · 2025Article
- Comparative Analysis of Influenza Epidemiology Before and After the COVID-19 Pandemic in Argentina (2018-2019 vs. 2022-2023).Influenza and other respiratory viruses · 2025Article
- Family matters: influenza vaccination uptake and associated factors in children aged 6 months-6 years.Frontiers in public health · 2025Article
- Observational
- Caregiver Burden among Patients with Influenza or Influenza-like Illness (ILI): A Systematic Literature Review.Healthcare (Basel, Switzerland) · 2024Review
- mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020.Frontiers in immunology · 2024Article
- Article
- Epidemiology of influenza over a ten-year period in Belgium: overview of the historical and current evidence.Virology journal · 2023Review
- Article
Corrections and comments
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Authors and funding
12 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfluenza is a major cause of respiratory illness in young children. Assessing the impact of infection on children and the community is required to guide immunisation policies.
objectivesTo describe the impact of laboratory-proven influenza in young children and to compare its impact with that of other respiratory viruses on the child, their family and the health care system.
methodsPreschool children presenting for care or admission to a tertiary paediatric hospital during the 2008-2014 influenza seasons were tested for respiratory virus by polymerase chain reaction and culture. Parental surveys were used to determine the impact of infection on illness duration, medication use, absenteeism and health service utilisation. Multivariate regression analyses were used to assess the impact of influenza and to evaluate the association between influenza status and outcomes.
resultsAmong 1191 children assessed, 238 had influenza. Among children with influenza, 87.8% were administered antipyretics and 40.9% antibiotics. 28.6% had secondary complications. 65.4% of children missed school/day care, and 53.4% of parents missed work. When influenza and other viruses were compared, significant differences were noted including duration of illness (influenza: 9.54 days, other viruses: 8.50 days; P = 0.005) and duration of absenteeism for both the child (23.1 vs 17.3 hours; P = 0.015) and their parents (28.5 vs 22.7 hours; P = 0.012).
conclusionsInfluenza infection in young children has a significant impact on medication use, absenteeism and the use of health care service. Significant differences are identified when compared with other ILI. These data demonstrate that influenza prevention strategies including immunisation are likely to have wide and significant impacts.
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