Evidence map›Paper›PMID 30137592›Full record

ArticleRheumatology (Oxford, England)2018

Risk of human papillomavirus infection in women with rheumatic disease: cervical cancer screening and prevention.

Seoyoung C Kim, Sarah Feldman, Anna-Barbara Moscicki

Open access · bronzeAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Review
  4. Vaccination Update and Specific Concerns for RA.Current rheumatology reports · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Seoyoung C KimDivision of Pharmacoepidemiology and Pharmacoeconomics.
Sarah FeldmanDepartment of Obstetrics Gynecology & Reproductive Biology, Brigham and Women's Hospital, Boston, MA.
Anna-Barbara MoscickiDepartment of Pediatrics, UCSF School of Medicine, San Francisco, CA, USA.
Brigham and Women's Hospital · USPharmacoeconomics and Health Outcomes Research Iberia (Spain) · ESUniversity of California, San Francisco · US

Funding

International Conference on Reproduction, Pregnancy, and Rheumatic DiseaseR13AR070007 · NIAMS · DUKE UNIVERSITY · PI CLOWSE, MEGAN E.B. · 2016 to 2016
$15k
NIAMS NIH HHS R13 AR070007
6 · The paper itself

Abstract

Human Papillomavirus (HPV) is the most common sexually transmitted infection in the USA, with over 14 million people acquiring HPV each year. HPV is also the cause of most anogenital cancers. About 90% of HPV infections spontaneously resolve over 3 years. However, about 10% remain as persistent infection defined as repeatedly detected in cervical samples. As HPV is controlled by local and systemic immune responses, individuals with immunosuppression are at risk for cervical cancer. It is hypothesized that immunosuppressed individuals are more likely to have HPV persistence, which is necessary for malignant transformation. Accordingly, women with rheumatic diseases such as SLE and RA are likely vulnerable to HPV infection and the progression of cervical disease. The HPV vaccine, given as a series of vaccinations, is safe and effective that can prevent HPV infection and cervical cancer. There is no contraindication to HPV vaccination for women to age 26 with rheumatic disease, as it is not live. As in the general population, timing is key for the efficacy of the HPV vaccine as the goal is to vaccinate prior to sexual debut and exposure to HPV. There are no formal recommendations for cervical cancer screening in women with rheumatic disease but recommendations for the HIV-positive population can be adopted, meaning to screen with a Pap test annually for three consecutive years and if all normal, to extend the interval to every 3 years with the option of co-testing with HPV at 30 years and older.

Indexed as

Immunocompromised HostPapillomaviridaeEarly Detection of CancerFemaleHumansMass ScreeningPapillomavirus InfectionsPapillomavirus VaccinesRheumatic DiseasesRisk FactorsUterine Cervical NeoplasmsPapillomavirus Vaccines

Identifiers

PMID30137592
PMCPMC6099129
OpenAlexW2888676303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.