Evidence map›Paper›PMID 30137591›Full record

ArticleRheumatology (Oxford, England)2018

Challenging cases in rheumatic pregnancies.

Cuoghi Edens, Bruna Costa Rodrigues, Marcela Ignacchiti Lacerda, Flavia Cunha Dos Santos, Guilherme R De Jesús, Nilson Ramires De Jesús, Roger A Levy, Cianna Leatherwood, Jess Mandel, Bonnie Bermas

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Rheumatology (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Cuoghi EdensDivision of Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children's Hospital.
Bruna Costa RodriguesDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Marcela Ignacchiti LacerdaDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Flavia Cunha Dos SantosDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Guilherme R De JesúsDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Nilson Ramires De JesúsDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Roger A LevyDepartment of Obstetrics, Hospital University Pedro Ernesto - Universidade do Estado do Rio de Janeiro, Rio de Janiero, Brazil.
Cianna LeatherwoodDivision of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA.
Jess MandelDivision of Pulmonary, Critical Care and Sleep Medicine, University of California San Diego School of Medicine, San Diego, CA.
Bonnie BermasDivision of Rheumatic Diseases, University of Texas Southwestern, Dallas, TX, USA.
Universidade do Estado do Rio de Janeiro · BRBrigham and Women's Hospital · USHospital Universitário Pedro Ernesto · BRThe University of Texas Southwestern Medical Center · USUniversity Hospitals of Cleveland · USUniversity of California System · US

Funding

International Conference on Reproduction, Pregnancy, and Rheumatic DiseaseR13AR070007 · NIAMS · DUKE UNIVERSITY · PI CLOWSE, MEGAN E.B. · 2016 to 2016
$15k
NIAMS NIH HHS R13 AR070007
6 · The paper itself

Abstract

This article describes three complicated cases in rheumatology and pregnancy. The first case elucidates the challenges in treating SLE in conjunction with pulmonary arterial hypertension, while the second case features an SLE-affected pregnancy with development of portal hypertension secondary to portal vein thrombosis related to APS. The third case is a pregnant woman with stable SLE who developed thrombotic microangiopathy caused by atypical haemolytic uraemic syndrome, and failed to improve despite multiple measures including biopsy and elective preterm delivery. There are grave and unique challenges for women with autoimmune disease, but adverse outcomes can sometimes be avoided with careful and multidisciplinary medical management. Pre-conception counselling with regard to medications and disease treatment should also include discussion of the advisability of pregnancy, which may be difficult for a patient, but present the best course for optimizing health outcomes.

Indexed as

AdultAtypical Hemolytic Uremic SyndromeFemaleHumansHypertension, PortalHypertension, PulmonaryLupus Erythematosus, SystemicPortal VeinPregnancyPregnancy Complications, CardiovascularPregnancy Complications, HematologicPregnancy OutcomeThrombotic MicroangiopathiesVenous ThrombosisYoung Adult

Identifiers

PMID30137591
PMCPMC6099127
OpenAlexW2888433739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.