SynthesisNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2018
Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper.
Synthesis in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 88 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation of Contrast Enhanced Ultrasound (CEUS) for the Assessment of Renal Perfusion Using Renal Magnetic Resonance Imaging (MRI), and Its Application in Acute Kidney Injury (AKI)
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
Who cites it
88 citing papers in PubMed, 4 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- The value of functional magnetic resonance imaging in the evaluation of diabetic kidney disease: a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper.Magma (New York, N.Y.) · 2020Pooled it
- Magnetic resonance imaging T1- and T2-mapping to assess renal structure and function: a systematic review and statement paper.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018Pooled it
- Free-Breathing Arterial Spin Labeling MRI of the Kidney Using Flow-Sensitive-Alternating Inversion Recovery With Golden-Angle Radial Sampling.NMR in biomedicine · 2026Article
- Capability of arterial spin labeling combined with morphological characteristics to distinguish early- and mid-stage chronic kidney disease: a prospective study on 5 T MRI.Quantitative imaging in medicine and surgery · 2026Article
- ASL, DTI, and T1 mapping in identifying immune and non-immune pathogenic factors of chronic allograft injury.Quantitative imaging in medicine and surgery · 2026Article
- Multiparametric MR Imaging for Evaluating Renal Function and Microstructure.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Review
- Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion.Artificial organs · 2026Article
- Automated Coregistered Segmentation for Volumetric Analysis of Multiparametric Renal MRI.Magnetic resonance in medicine · 2026Article
- Multimodal Magnetic Resonance Imaging in Diabetic Kidney Disease: From Pathophysiological Insights to Clinical Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Contrast-free functional MRI for assessing renal involvement in patients with ANCA-associated vasculitis.BMC nephrology · 2026Article
- Insight into Kidney Function and Microstructure Through Renal MRI-Review of the Literature.Bioengineering (Basel, Switzerland) · 2026Review
- Quantitative dynamic contrast-enhanced magnetic resonance imaging for renal perfusion measurement in autosomal dominant polycystic kidney disease.Quantitative imaging in medicine and surgery · 2026Article
- Early diagnosis of radiation-induced renal injury: from lagging indicators to multimodal, pre-fibrotic detection.Frontiers in cell and developmental biology · 2026Review
- Assessment of renal insufficiency in patients with renal artery stenosis by multiparametric magnetic resonance imaging.Renal failure · 2025Article
- Measurement of renal cortex perfusion: A direct comparison of arterial spin labelling magnetic resonance imaging and [Magnetic resonance in medicine · 2025Article
- Estimation of multicomponent flow in the kidney with multi-b-value spectral diffusion.Magnetic resonance in medicine · 2025Article
- Longitudinal assessment of renal allograft function in donors and pediatric recipients by arterial spin labeling MRI perfusion quantification.Scientific reports · 2025Article
- Influence of Field Strength, Sex, and Age on Pseudo-Continuous Arterial Spin Labeling and TJournal of magnetic resonance imaging : JMRI · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 6 institutions in 4 countries.
Funding
Abstract
Renal perfusion provides the driving pressure for glomerular filtration and delivers the oxygen and nutrients to fuel solute reabsorption. Renal ischaemia is a major mechanism in acute kidney injury and may promote the progression of chronic kidney disease. Thus, quantifying renal tissue perfusion is critically important for both clinicians and physiologists. Current reference techniques for assessing renal tissue perfusion have significant limitations. Arterial spin labelling (ASL) is a magnetic resonance imaging (MRI) technique that uses magnetic labelling of water in arterial blood as an endogenous tracer to generate maps of absolute regional perfusion without requiring exogenous contrast. The technique holds enormous potential for clinical use but remains restricted to research settings. This statement paper from the PARENCHIMA network briefly outlines the ASL technique and reviews renal perfusion data in 53 studies published in English through January 2018. Renal perfusion by ASL has been validated against reference methods and has good reproducibility. Renal perfusion by ASL reduces with age and excretory function. Technical advancements mean that a renal ASL study can acquire a whole kidney perfusion measurement in less than 5-10 min. The short acquisition time permits combination with other MRI techniques that might inform drug mechanisms and renal physiology. The flexibility of renal ASL has yielded several variants of the technique, but there are limited data comparing these approaches. We make recommendations for acquiring and reporting renal ASL data and outline the knowledge gaps that future research should address.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.