SynthesisNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2018
Diffusion-weighted magnetic resonance imaging to assess diffuse renal pathology: a systematic review and statement paper.
Synthesis in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 117 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sub-project of the Clinical Protocol ACH471-205 "An Open-Label Phase 2 Proof-of-Concept Study in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN) Treated With ACH-0144471"
Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, Empagliflozin
Who cites it
117 citing papers in PubMed, 5 syntheses or guidelines pooled it, 173 citations in OpenAlex.
- Multiparametric functional MRI for detection of early renal allograft dysfunction after kidney transplantation: a systematic review and meta-analysis.BMC nephrology · 2026Pooled it
- ESR Essentials: Perfusion MRI-practice recommendations by the European Society for Magnetic Resonance in Medicine and Biology.European radiology · 2026Guideline
- Phase-contrast magnetic resonance imaging to assess renal perfusion: a systematic review and statement paper.Magma (New York, N.Y.) · 2020Pooled it
- Consensus-based technical recommendations for clinical translation of renal diffusion-weighted MRI.Magma (New York, N.Y.) · 2020Pooled it
- Arterial spin labelling MRI to measure renal perfusion: a systematic review and statement paper.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018Pooled it
- Multi-Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial.Diabetes, obesity & metabolism · 2026Trial
- Diffusion Tensor Imaging of the Kidney: Design and Evaluation of a Reliable Processing Pipeline.Scientific reports · 2019Trial
- Tubulointerstitial inflammation in glomerular diseases: mechanistic pathways, prognostic value, and translational therapeutic targets.Renal failure · 2026Review
- Navigating the diagnostic 'gray zone': prospective evaluation of an integrated MRI-Biomarker model for renal allograft triage.Annals of medicine · 2026Article
- Renal elastography in kidney disease: Current evidence, limitations, and future directions.World journal of nephrology · 2026Review
- ASL, DTI, and T1 mapping in identifying immune and non-immune pathogenic factors of chronic allograft injury.Quantitative imaging in medicine and surgery · 2026Article
- Added value of restricted diffusion in acute pyelonephritis: Two cases with different clinical presentations.Radiology case reports · 2026Article
- Intra- and interobserver variability in renal multiparametric magnetic resonance imaging: T1 mapping, diffusion-weighted imaging, arterial spin labeling, blood oxygen level-dependent and renal artery flow measurements utilizing manual segmentation.Quantitative imaging in medicine and surgery · 2026Article
- Magnetic Resonance Imaging Evaluation of Functional Differences Between In Vivo Human Kidneys and Discarded Human Kidneys During Ex Vivo Normothermic Machine Perfusion.Artificial organs · 2026Article
- Volumetric MRI assessment of perirenal hematoma following biopsy of native and transplanted kidneys.International urology and nephrology · 2026Article
- Automated Coregistered Segmentation for Volumetric Analysis of Multiparametric Renal MRI.Magnetic resonance in medicine · 2026Article
- Toward Optimized Intravoxel Incoherent Motion (IVIM) and Compartmental T2 Mapping in Abdominal Organs.Magnetic resonance in medicine · 2026Article
- Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations.Journal of magnetic resonance imaging : JMRI · 2026Article
- Magnetic resonance elastography of the pediatric kidney: technical considerations and emerging clinical applications.Pediatric radiology · 2026Review
- Cardiac-Gated Diffusion-Weighted Magnetic Resonance Imaging Assessment of Kidney Function in Patients With Kidney Cancer.Kidney international reports · 2026Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 10 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diffusion-weighted magnetic resonance imaging (DWI) is a non-invasive method sensitive to local water motion in the tissue. As a tool to probe the microstructure, including the presence and potentially the degree of renal fibrosis, DWI has the potential to become an effective imaging biomarker. The aim of this review is to discuss the current status of renal DWI in diffuse renal diseases. DWI biomarkers can be classified in the following three main categories: (i) the apparent diffusion coefficient-an overall measure of water diffusion and microcirculation in the tissue; (ii) true diffusion, pseudodiffusion and flowing fraction-providing separate information on diffusion and perfusion or tubular flow; and (iii) fractional anisotropy-measuring the microstructural orientation. An overview of human studies applying renal DWI in diffuse pathologies is given, demonstrating not only the feasibility and intra-study reproducibility of DWI but also highlighting the need for standardization of methods, additional validation and qualification. The current and future role of renal DWI in clinical practice is reviewed, emphasizing its potential as a surrogate and monitoring biomarker for interstitial fibrosis in chronic kidney disease, as well as a surrogate biomarker for the inflammation in acute kidney diseases that may impact patient selection for renal biopsy in acute graft rejection. As part of the international COST (European Cooperation in Science and Technology) action PARENCHIMA (Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease), aimed at eliminating the barriers to the clinical use of functional renal magnetic resonance imaging, this article provides practical recommendations for future design of clinical studies and the use of renal DWI in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.