Evidence map›Paper›PMID 30137498›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2018

Identification of validated case definitions for medical conditions used in primary care electronic medical record databases: a systematic review.

Kerry A McBrien, Sepideh Souri, Nicola E Symonds, Azin Rouhi, Brendan C Lethebe, Tyler S Williamson, Stephanie Garies, Richard Birtwhistle, Hude Quan, Gabriel E Fabreau and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  10. Validation of adult asthma case definitions for primary care sentinel surveillance.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
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  18. Machine learning approaches for electronic health records phenotyping: a methodical review.Journal of the American Medical Informatics Association : JAMIA · 2023
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kerry A McBrienDepartment of Family Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Sepideh SouriDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Nicola E SymondsFaculty of Science, University of British Columbia, Vancouver, Canada.
Azin RouhiFaculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.
Brendan C LethebeDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Tyler S WilliamsonDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Stephanie GariesDepartment of Family Medicine, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Richard BirtwhistleDepartment of Family Medicine, Faculty of Health Sciences, Queen's University, Kingston, Canada.
Hude QuanDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Gabriel E FabreauDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Paul E RonksleyDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Data derived from primary care electronic medical records (EMRs) are being used for research and surveillance. Case definitions are required to identify patients with specific conditions in EMR data with a degree of accuracy. The purpose of this study is to identify and provide a summary of case definitions that have been validated in primary care EMR data. Materials and Methods: We searched MEDLINE and Embase (from inception to June 2016) to identify studies that describe case definitions for clinical conditions in EMR data and report on the performance metrics of these definitions. Results: We identified 40 studies reporting on case definitions for 47 unique clinical conditions. The studies used combinations of International Classification of Disease version 9 (ICD-9) codes, Read codes, laboratory values, and medications in their algorithms. The most common validation metric reported was positive predictive value, with inconsistent reporting of sensitivity and specificity. Discussion: This review describes validated case definitions derived in primary care EMR data, which can be used to understand disease patterns and prevalence among primary care populations. Limitations include incomplete reporting of performance metrics and uncertainty regarding performance of case definitions across different EMR databases and countries. Conclusion: Our review found a significant number of validated case definitions with good performance for use in primary care EMR data. These could be applied to other EMR databases in similar contexts and may enable better disease surveillance when using clinical EMR data. Consistent reporting across validation studies using EMR data would facilitate comparison across studies. Systematic review registration: PROSPERO CRD42016040020 (submitted June 8, 2016, and last revised June 14, 2016).

Indexed as

Databases, FactualElectronic Health RecordsPrimary Health CareDiseaseHumansPublic Health SurveillanceReproducibility of Results

Identifiers

PMID30137498
PMCPMC7646917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.