ArticleJournal of the International Neuropsychological Society : JINS2018
Evidence for Reduced Autobiographical Memory Episodic Specificity in Cognitively Normal Middle-Aged and Older Individuals at Increased Risk for Alzheimer's Disease Dementia.
Article in Journal of the International Neuropsychological Society : JINS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Autobiographical memory in Alzheimer's disease: a systematic review.Frontiers in neurology · 2025Pooled it
- In here and out there: Evidence that age-related differences in memory specificity are attenuated in natural social conversations.Journal of experimental psychology. General · 2026Article
- Modeling memories, predicting prospections: Automated scoring of autobiographical detail narration using large language models.Behavior research methods · 2025Article
- Self-Concept in Mild Cognitive Impairment and Mild Dementia due to Alzheimer's Disease Is Affected on Tests of Self-Generated Statements.Scandinavian journal of psychology · 2025Article
- Shape of the past: Revealing detail arcs while narrating memories of autobiographical life events across the lifespan.Psychonomic bulletin & review · 2025Article
- Direct access to specific autobiographical memories is lower in healthy middle-aged to older adult Apolipoprotein E ε4 carriers compared to non-carriers.Journal of neuropsychology · 2025Article
- The Usability and Effect of a Novel Intelligent Rehabilitation Exergame System on Quality of Life in Frail Older Adults: Prospective Cohort Study.JMIR serious games · 2025Article
- Retrieving autobiographical memories in autobiographical contexts: are age-related differences in narrated episodic specificity present outside of the laboratory?Psychological research · 2024Article
- Multidimensional assessment of time perception along the continuum of Alzheimer's Disease and evidence of alterations in subjective cognitive decline.Scientific reports · 2023Article
- Past and future episodic detail retrieval is reduced among clinically normal older adults at higher genetic risk for late-onset Alzheimer's disease.Neuropsychology · 2023Article
- Tai Chi exercise improves working memory capacity and emotion regulation ability.Frontiers in psychology · 2023Article
- Largely intact memory for spatial locations during navigation in an individual with dense amnesia.Neuropsychologia · 2022Article
- Remembering past challenges to feel better today: Role of neural dedifferentiation and autobiographical integration in late-life reappraisal.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2022Review
- Is This Phishing? Older Age Is Associated With Greater Difficulty Discriminating Between Safe and Malicious Emails.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021Article
- Autobiographical Memory Fluency Reductions in Cognitively Unimpaired Middle-Aged and Older Adults at Increased Risk for Alzheimer's Disease Dementia.Journal of the International Neuropsychological Society : JINS · 2021Article
- Searching for the past: Exploring the dynamics of direct and generative autobiographical memory reconstruction among young and cognitively normal older adults.Memory & cognition · 2021Article
- Characteristics of Neural Network Changes in Normal Aging and Early Dementia.Frontiers in aging neuroscience · 2021Review
- Older Adults Show Reduced Spatial Precision but Preserved Strategy-Use During Spatial Navigation Involving Body-Based Cues.Frontiers in aging neuroscience · 2021Article
- Memory precision of object-location binding is unimpaired inBrain communications · 2021Article
- A profile of brain reserve in adults at genetic risk of Alzheimer's disease.Alzheimer's & dementia (Amsterdam, Netherlands) · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
objectivesAlzheimer's disease (AD) typically eludes clinical detection for years, if not decades. The identification of subtle cognitive decline associated with preclinical AD would not only advance understanding of the disease, but also provide clinical targets to assess preventative and early intervention treatments. Disrupted retrieval of detailed episodic autobiographical memories may be a sensitive indicator of subtle cognitive decline, because this type of memory taxes a core neural network affected by preclinical AD neuropathology.
methodsTo begin to address this idea, we assessed the episodic specificity of autobiographical memories retrieved by cognitively normal middle-aged and older individuals who are carriers of the apolipoprotein E ε4 allele - a population at increased risk for subtle cognitive decline related to neuropathological risk factors for AD. We compared the ε4 carriers to non-carriers of ε4 similar in age, education, and gender.
resultsThe ε4 carriers did not perform worse than the non-carriers on a comprehensive battery of neuropsychological tests. In contrast, as a group, the ε4 carriers generated autobiographical memories that were reduced in "internal" or episodic details relative to non-carriers.
conclusionsThese findings support the notion that reduced autobiographical episodic detail generation may be a marker of subtle cognitive decline associated with AD. (JINS, 2018, 24, 1073-1183).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.