Evidence map›Paper›PMID 30136897›Full record

ArticleNeurorehabilitation and neural repair2018

Motor Impairment-Related Alterations in Biceps and Triceps Brachii Fascicle Lengths in Chronic Hemiparetic Stroke.

Christa M Nelson, Wendy M Murray, Julius P A Dewald

Abstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  11. Development of DTI Based Probabilistic Tractography Methods to Characterize Arm Muscle Architecture in Individuals Post Hemiparetic Stroke.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2021
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  15. Variability ofFrontiers in physiology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christa M Nelson1 University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-4811-8561
Wendy M Murray2 Northwestern University, Evanston, IL, USA.
Julius P A Dewald2 Northwestern University, Evanston, IL, USA.

Funding

EFFECT OF NEURAL CONSTRAINTS ON MOVEMENT IN STROKER01HD039343 · NICHD · REHABILITATION INSTITUTE OF CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2000 to 2026
$6.0M
Interdisciplinary Graduate Education in Movement and Rehabilitation Sciences-RenewalT32EB009406 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2009 to 2026
$2.2M
Motor impairment related changes in muscles properties in chronic strokeR01HD084009 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, MURRAY, WENDY M · 2015 to 2018
$1.8M
NIBIB NIH HHS T32 EB009406NICHD NIH HHS R01 HD039343NICHD NIH HHS R01 HD084009
6 · The paper itself

Abstract

Poststroke deficits in upper extremity function occur during activities of daily living due to motor impairments of the paretic arm, including weakness and abnormal synergies, both of which result in altered use of the paretic arm. Over time, chronic disuse and a resultant flexed elbow posture may result in secondary changes in the musculoskeletal system that may limit use of the arm and impact functional mobility. This study utilized extended field-of-view ultrasound to measure fascicle lengths of the biceps (long head) and triceps (distal portion of the lateral head) brachii in order to investigate secondary alterations in muscles of the paretic elbow. Data were collected from both arms in 11 individuals with chronic hemiparetic stroke, with moderate to severe impairment as classified by the Fugl-Meyer assessment score. Across all participants, significantly shorter fascicles were observed in both biceps and triceps brachii ( P < .0005) in the paretic limb under passive conditions. The shortening in paretic fascicle length relative to the nonparetic arm measured under passive conditions remained observable during active muscle contraction for the biceps but not for the triceps brachii. Finally, average fascicle length differences between arms were significantly correlated to impairment level, with more severely impaired participants showing greater shortening of paretic biceps fascicle length relative to changes seen in the triceps across all elbow positions ( r = -0.82, P = .002). Characterization of this secondary adaptation is necessary to facilitate development of interventions designed to reduce or prevent the shortening from occurring in the acute stages of recovery poststroke.

Indexed as

AdultAgedArmFemaleHumansMaleMiddle AgedMuscle ContractionMuscle, SkeletalParesisRange of Motion, ArticularStrokeUltrasonographyYoung Adultfascicle lengthmuscle adaptationmuscle architecturestrokeultrasonographyupper extremity

Identifiers

PMID30136897
PMCPMC6296776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.