Evidence map›Paper›PMID 30136299›Full record

ArticleNeurourology and urodynamics2018

The Prevention of Lower Urinary Tract Symptoms (PLUS) in girls and women: Developing a conceptual framework for a prevention research agenda.

Sonya S Brady, Tamara G Bavendam, Amanda Berry, Cynthia S Fok, Sheila Gahagan, Patricia S Goode, Cecilia T Hardacker, Jeni Hebert-Beirne, Cora E Lewis, Jessica B Lewis and 6 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Neurourology and urodynamics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04016298 (Validation of Bladder Health Instrument for Evaluation in Women), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04016298 completednot on this mapstarted 2019, after this paper: background citation

Validation of Bladder Health Instrument for Evaluation in Women

TypeobservationalSponsorUniversity of MinnesotaRan2019 to 2022Enrolled1,222ConditionsLower Urinary Tract Symptoms
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 65 citations in OpenAlex.

  1. Toileting and Bladder Health in the Gig Economy.Neurourology and urodynamics · 2025
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  11. Psychosocial Factors Associated with Lower Urinary Tract Symptoms One Year Postpartum.International journal of environmental research and public health · 2023
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 1 country.

Sonya S BradyDivision of Epidemiology & Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota.ORCID 0000-0001-8660-9308
Tamara G BavendamNational Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
Amanda BerryDivision of Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Cynthia S FokDepartment of Urology, University of Minnesota Medical School, Minneapolis, Minnesota.
Sheila GahaganDivision of Academic General Pediatrics, University of California San Diego, San Diego, California.
Patricia S GoodeDivision of Gerontology, Geriatrics, and Palliative Care, University of Alabama at Birmingham, Birmingham, Alabama.
Cecilia T HardackerHoward Brown Health, Chicago, Illinois.
Jeni Hebert-BeirneDivision of Community Health Sciences, University of Illinois at Chicago, School of Public Health, Chicago, Illinois.
Cora E LewisDepartment of Epidemiology, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama.
Jessica B LewisYale School of Public Health, New Haven, Connecticut.
Lisa Kane LowSchool of Nursing, Women's Studies, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan.
Jerry L LowderDivision of Female Pelvic Medicine and Reconstructive Surgery, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Mary H PalmerSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Jean F WymanSchool of Nursing, University of Minnesota, Minneapolis, Minnesota.
Emily S LukaczDivision of Female Pelvic Medicine & Reconstructive Surgery, University of California San Diego, San Diego, California.
Prevention of Lower Urinary Tract Symptoms (PLUS) Research ConsortiumDivision of Female Pelvic Medicine & Reconstructive Surgery, University of California San Diego, San Diego, California.
University of Alabama at Birmingham · USUniversity of California San Diego · USUniversity of Minnesota · USChildren's Hospital of Philadelphia · USHoward Brown Health Center · USNational Institutes of Health · USUniversity of Illinois Chicago · USUniversity of Michigan · USUniversity of Minnesota Medical Center · USUniversity of North Carolina at Chapel Hill · USWashington University in St. Louis · USYale New Haven Health System · US

Funding

Prevention of Lower Urinary Tract Symptoms in Women: Bladder Health Scientific and Data Coordinating Center (PLUS-SDCC) (U01)U01DK106786 · NIDDK · UNIVERSITY OF MINNESOTA · PI HARLOW, BERNARD L, RUDSER, KYLE · 2015 to 2019
$8.4M
University of Pennsylvania+ PLUS Clinical Center (PENN+PLUS CC)U01DK106892 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI NEWMAN, DIANE K., SMITH, ARIANA L · 2015 to 2024
$5.4M
PLUS Loyola Clinical CenterU01DK106898 · NIDDK · LOYOLA UNIVERSITY CHICAGO · PI BRUBAKER, LINDA, FITZGERALD, COLLEEN MARIE · 2015 to 2024
$4.7M
Prevention of LUTS: Bladder Health Clinical Center, UC San Diego SiteU01DK106827 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LACOURSIERE, DAPHNE YVETTE, LUKACZ, EMILY S. · 2015 to 2024
$4.5M
Pathways to LUTS Prevention: A Model for Public Education, Behavioral Skills, and Early DetectionU01DK106858 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI MCGWIN, GERALD · 2015 to 2024
$4.5M
LUTS PREVENTION IN ADOLESCENT GIRLS AND WOMEN ACROSS THE LIFESPANU01DK106853 · NIDDK · WASHINGTON UNIVERSITY · PI SUTCLIFFE, SIOBHAN · 2015 to 2024
$4.0M
The Truly Healthy Bladder: Understanding Normal As A Pathway To Prevention Of Lower Urinary Tract Symptoms In WomenU01DK106893 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOW, LISA KANE · 2015 to 2024
$3.8M
Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium Yale Clinical Research CenterU01DK106908 · NIDDK · YALE UNIVERSITY · PI RICKEY, LESLIE M. · 2015 to 2024
$3.5M
National Institutes of Health (NIH) U01DK106786National Institutes of Health (NIH) U01DK106827National Institutes of Health (NIH) U01DK106853National Institutes of Health (NIH) U01DK106858National Institutes of Health (NIH) U01DK106892National Institutes of Health (NIH) U01DK106893National Institutes of Health (NIH) U01DK106898National Institutes of Health (NIH) U01DK106908NIA NIH HHSNIDDK NIH HHS U01 DK106786NIDDK NIH HHS U01 DK106827NIDDK NIH HHS U01 DK106853NIDDK NIH HHS U01 DK106858NIDDK NIH HHS U01 DK106892NIDDK NIH HHS U01 DK106893NIDDK NIH HHS U01 DK106898NIDDK NIH HHS U01 DK106908NIH Office of Behavioral and Social Sciences ResearchNIH Office of Research on Women's Health
6 · The paper itself

Abstract

aimsThe Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium was established by the National Institutes of Health in 2015 to expand research beyond the detection and treatment of lower urinary tract symptoms (LUTS) to the promotion and preservation of bladder health and prevention of LUTS in girls and women. While many multi-disciplinary scientific networks focus on pelvic floor dysfunction and LUTS, the PLUS Consortium stands alone in its focus on prevention. This article describes the PLUS approach to developing a conceptual framework to guide the Consortium's initial prevention research agenda.

methodsThe conceptual framework was informed by traditional social ecological models of public health, biopsychosocial models of health, Glass and McAtee's Society-Behavior-Biology Nexus, and the World Health Organization's conceptual framework for action on the social determinants of health.

resultsThe PLUS conceptual framework provides a foundation for developing prevention interventions that have the greatest likelihood of promoting and preserving bladder health among diverse populations.

conclusionsPLUS Consortium work is premised on the notion that programs, practices, and policies designed to promote health will have optimal impact if the conceptual foundation upon which efforts are based is comprehensive and informed by multiple disciplines. The PLUS conceptual framework is broadly applicable to domains of health that have historically focused on the treatment of illness and symptoms rather than the promotion of health. It is also applicable to domains of health that have been examined from a predominantly biological or social ecological perspective, without integration of both perspectives.

Indexed as

Health PromotionAdolescentAdultFemaleGuidelines as TopicHealth StatusHumansLower Urinary Tract SymptomsPublic HealthResearchSocial EnvironmentUrinary BladderWorld Health OrganizationYoung Adultbladder healthconceptual frameworkgirlslower urinary tract symptomspreventionsocial ecologywomen

Identifiers

PMID30136299
PMCPMC6451314
OpenAlexW2783951531

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.