Evidence map›Paper›PMID 30136119›Full record

ArticleNeuroradiology2018

Diffusion tensor imaging of the optic disc in idiopathic intracranial hypertension.

Ahmed Abdel Khalek Abdel Razek, Nihal Batouty, Wesam Fathy, Rania Bassiouny

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Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ahmed Abdel Khalek Abdel RazekDepartment of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt. arazek@mans.edu.eg.ORCID http://orcid.org/0000-0002-9613-5932
Nihal BatoutyDepartment of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt.
Wesam FathyDepartment of Neurology, Mansoura Faculty of Medicine, Mansoura, Egypt.
Rania BassiounyDepartment of Ophthalmology, Mansoura Faculty of Medicine, Mansoura, Egypt.
Mansoura University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study optic disc in idiopathic intracranial hypertension (IIH) with diffusion tensor imaging.

methodsProspective study was carried out on 31 consecutive patients with IIH and 17 age and sex-matched controls that underwent diffusion tensor imaging of optic nerve. Fractional anisotropy (FA) and mean diffusivity (MD) of optic disc were measured by two readers. Grades of papilledema and visual field defects were evaluated by ophthalmologist.

resultsFA of optic disc was significantly lower in IIH than controls (p = 0.001) with excellent inter-observer agreement (K = 0.93) of both readers. The cutoff FA used to differentiating IIH from controls were 0.28 and 0.29 with area under curve (AUC) of 0.921 and 0.914, accuracy 92% and 91%, and sensitivity 97% and 96%. MD of optic disc were significantly higher in IIH than in controls (p = 0.001) with excellent inter-observer agreement (K = 0.91) of both readers. The cutoff MD used to differentiating IIH from controls was 1.51 and 1.22 × 10

conclusionDiffusion tensor imaging parameters of optic disc are non-invasive reliable imaging parameters that can be used for diagnosis of IIH and well correlated with papilledema and visual field defects.

Indexed as

AdultAnisotropyCase-Control StudiesDiffusion Tensor ImagingFemaleHumansImage Interpretation, Computer-AssistedMaleOptic DiskProspective StudiesPseudotumor CerebriSensitivity and SpecificityVision TestsDiffusion tensor imagingIdiopathic intracranial hypertensionOptic disc

Identifiers

PMID30136119
OpenAlexW2888090793

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.