Evidence map›Paper›PMID 30135866›Full record

ArticleeNeuro

Combinatorial Expression of

Daniel J Kramer, Davide Risso, Polina Kosillo, John Ngai, Helen S Bateup

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 76 citations in OpenAlex.

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  18. Increased sucrose consumption in mice gene-targeted forFrontiers in molecular neuroscience · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel J KramerDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
Davide RissoDivision of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine, New York, NY 10065.ORCID 0000-0001-8508-5012
Polina KosilloDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
John NgaiDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.
Helen S BateupDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720.ORCID 0000-0002-0135-0972
University of California, Berkeley · USCornell University · US

Funding

THE MOLECULAR BASIS OF CELL FUNCTIONT32GM007232 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BILDER, DAVID, UNAL, ELCIN · 1985 to 2022
$36.4M
Classification of Cortical Neurons by Single Cell TranscriptomicsU01MH105979 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI NGAI, JOHN J. · 2014 to 2016
$4.5M
NIGMS NIH HHS T32 GM007232NIMH NIH HHS U01 MH105979
6 · The paper itself

Abstract

Midbrain dopamine neurons project to numerous targets throughout the brain to modulate various behaviors and brain states. Within this small population of neurons exists significant heterogeneity based on physiology, circuitry, and disease susceptibility. Recent studies have shown that dopamine neurons can be subdivided based on gene expression; however, the extent to which genetic markers represent functionally relevant dopaminergic subpopulations has not been fully explored. Here we performed single-cell RNA-sequencing of mouse dopamine neurons and validated studies showing that

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsDopaminergic NeuronsFemaleGastrin-Releasing PeptideIn Situ Hybridization, FluorescenceMaleMesencephalonMice, Inbred C57BLNerve Tissue ProteinsNeural PathwaysNucleus AccumbensSequence Analysis, RNAVentral Tegmental AreaBasic Helix-Loop-Helix ProteinsGastrin-Releasing PeptideNerve Tissue ProteinsNeurod6 protein, mouseCellular HeterogeneityDopamine NeuronsGrpNeurod6Retrograde TracingSingle-Cell RNA-SequencingVTA

Identifiers

PMID30135866
PMCPMC6104179
OpenAlexW2803110575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.