Evidence map›Paper›PMID 30135716›Full record

ReviewF1000Research2018

Recent advances in understanding the complexities of metastasis.

Jessica L Chitty, Elysse C Filipe, Morghan C Lucas, David Herrmann, Thomas R Cox, Paul Timpson

Abstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Pan-cancer drivers of metastasis.Molecular cancer · 2025
    Article
  6. Review
  7. Review
  8. Edaravone: A Novel Possible Drug for Cancer Treatment?International journal of molecular sciences · 2024
    Review
  9. Nanomedicine (London, England) · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jessica L Chitty *Garvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.ORCID 0000-0003-1776-1618
Elysse C Filipe *Garvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.
Morghan C LucasGarvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.ORCID 0000-0001-7654-9137
David HerrmannGarvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.
Thomas R CoxGarvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.ORCID 0000-0001-9294-1745
Paul TimpsonGarvan Institute of Medical Research & the Kinghorn Cancer Centre, Cancer Division, Sydney, NSW, 2010, Australia.ORCID 0000-0002-5514-7080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour metastasis is a dynamic and systemic process. It is no longer seen as a tumour cell-autonomous program but as a multifaceted and complex series of events, which is influenced by the intrinsic cellular mutational burden of cancer cells and the numerous bidirectional interactions between malignant and non-malignant cells and fine-tuned by the various extrinsic cues of the extracellular matrix. In cancer biology, metastasis as a process is one of the most technically challenging aspects of cancer biology to study. As a result, new platforms and technologies are continually being developed to better understand this process. In this review, we discuss some of the recent advances in metastasis and how the information gleaned is re-shaping our understanding of metastatic dissemination.

Indexed as

Neoplasm MetastasisAnimalsCell MovementHumansNeoplasm InvasivenessNeoplasmsNeoplastic Cells, CirculatingBiosensorsCancerCancer TherapyCirculating Tumour CellsColonisationDisseminated Tumour CellsDormancyExtracellular MatrixExtravasationIntravasationIntravital ImagingInvasionMetastasisMicroenvironmentMigrationMouse ModelsTumour Stroma

Identifiers

PMID30135716
PMCPMC6073095

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.