Evidence map›Paper›PMID 30135714›Full record

ReviewF1000Research2018

Tackling resistance: emerging antimalarials and new parasite targets in the era of elimination.

Emily S Mathews, Audrey R Odom John

Abstract readReview
In one paragraph

Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Optimization of diastereomeric dihydropyridines as antimalarials.European journal of medicinal chemistry · 2024
    Article
  5. Article
  6. Antimalarial drug discovery: progress and approaches.Nature reviews. Drug discovery · 2023
    Review
  7. Novel Therapeutics for Malaria.Pharmaceutics · 2023
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. An Overview of Drug Resistance in Protozoal Diseases.International journal of molecular sciences · 2019
    Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emily S MathewsDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-7723-4428
Audrey R Odom JohnDepartment of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

Infectious Diseases/Basic Microbial Pathogenic MechanismsT32AI007172 · NIAID · WASHINGTON UNIVERSITY · PI Daniel E. Goldberg, JENNIFER A PHILIPS · 1985 to 2026
$13.0M
MEP pathway resistance in Plasmodium falciparumR01AI103280 · NIAID · WASHINGTON UNIVERSITY · PI Audrey Ragan Odom John · 2013 to 2026
$5.5M
TARGETING ISPC TO TREAT MALARIAR21AI123808 · NIAID · WASHINGTON UNIVERSITY · PI ODOM JOHN, AUDREY RAGAN · 2016 to 2017
$440k
NIAID NIH HHS R01 AI103280NIAID NIH HHS R21 AI123808NIAID NIH HHS T32 AI007172
6 · The paper itself

Abstract

Malaria remains a significant contributor to global human mortality, and roughly half the world's population is at risk for infection with

Indexed as

AnimalsAntimalarialsDrug DiscoveryDrug ResistanceHumansMolecular Targeted TherapyParasitesAntimalarialsantimalarialdrug discoverydrug targetsPlasmodiumresistance

Identifiers

PMID30135714
PMCPMC6073090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.