Evidence map›Paper›PMID 30135687›Full record

ArticleFrontiers in immunology2018

APOBEC3G/3A Expression in Human Immunodeficiency Virus Type 1-Infected Individuals Following Initiation of Antiretroviral Therapy Containing Cenicriviroc or Efavirenz.

Daniela A Covino, Cristina Purificato, Laura Catapano, Clementina M Galluzzo, Maria Cristina Gauzzi, Stefano Vella, Eric Lefebvre, Star Seyedkazemi, Mauro Andreotti, Laura Fantuzzi

Abstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Dual CCR5/CCR2 targeting: opportunities for the cure of complex disorders.Cellular and molecular life sciences : CMLS · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniela A CovinoNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Cristina PurificatoNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Laura CatapanoNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Clementina M GalluzzoNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Maria Cristina GauzziNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Stefano VellaNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Eric LefebvreAllergan plc, South San Francisco, CA, United States.
Star SeyedkazemiAllergan plc, South San Francisco, CA, United States.
Mauro AndreottiNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Laura FantuzziNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3) family members are cytidine deaminases that play crucial roles in innate responses to retrovirus infection. The mechanisms by which some of these enzymes restrict human immunodeficiency virus type 1 (HIV-1) replication have been extensively investigated

Indexed as

Gene Expression RegulationHIV-1AdultAlkynesAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveAPOBEC-3G DeaminaseBenzoxazinesCD4 Lymphocyte CountCyclopropanesCytidine DeaminaseDisease ProgressionFemaleHIV InfectionsHumansImidazolesAlkynesAnti-HIV AgentsAPOBEC3A protein, humanAPOBEC-3G DeaminaseAPOBEC3G protein, humanBenzoxazinescenicrivirocCyclopropanesCytidine DeaminaseefavirenzImidazolesProteinsSulfoxidesantiretroviral therapyAPOBEC3AAPOBEC3Gcenicrivirocchronic inflammationdisease progression

Identifiers

PMID30135687
PMCPMC6092507

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.