ArticleScientific reports2018
Interhemispheric connectivity of primary sensory cortex is associated with motor impairment after stroke.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Application of Neuromodulation Techniques in the Treatment of Proprioceptive Disorders After Stroke: A Meta-Analysis of Randomized Controlled Trials.Neural plasticity · 2025Pooled it
- Transcranial static magnetic stimulation modulates sensory interhemispheric inhibition as revealed by somatosensory evoked potentials and high-frequency oscillations.Scientific reports · 2026Trial
- Multimodal assessment of a BCI system for stroke rehabilitation integrating motor imagery and motor attempts: a randomized controlled trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Post-task resting-state fMRI of walking-related neural activity in patients with stroke: immediate and delayed brain network dynamics.Annals of medicine · 2026Article
- On the impact of tactile processing on motor cortex: how touch shapes motor behaviour.Brain structure & function · 2026Review
- Cortical functional hierarchy disruption following subcortical stroke.BMC medicine · 2026Article
- The Role of Hemispheric Sensory Shifts: Impacts on Stretch Reflex and Motor Plasticity Post-Stroke.Medical hypotheses · 2025Article
- Post-stroke changes in brain structure and function can both influence acute upper limb function and subsequent recovery.NeuroImage. Clinical · 2025Article
- How the Somatosensory System Adapts to the Motor Change in Stroke: A Hemispheric Shift?Medical hypotheses · 2024Article
- Alteration of Cortical Somatosensory Feedback in Post-Stroke Movement Control.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2024Article
- Use of functional magnetic resonance imaging to identify cortical loci for lower limb movements and their efficacy for individuals after stroke.Journal of neuroengineering and rehabilitation · 2024Article
- Network Reorganization for Neurophysiological and Behavioral Recovery Following Stroke.Central nervous system agents in medicinal chemistry · 2024Review
- Relationship between resting-state functional connectivity and change in motor function after motor imagery intervention in patients with stroke: a scoping review.Journal of neuroengineering and rehabilitation · 2023Article
- Early functional connectivity alterations in contralesional motor networks influence outcome after severe stroke: a preliminary analysis.Scientific reports · 2023Article
- Neuroplasticity Following Stroke from a Functional Laterality Perspective: A fNIRS Study.Brain topography · 2023Article
- Post-Ischemic Reorganization of Sensory Responses in Cerebral Cortex.bioRxiv : the preprint server for biology · 2023Article
- Post-ischemic reorganization of sensory responses in cerebral cortex.Frontiers in neuroscience · 2023Article
- Longitudinal evaluation of the functional connectivity changes in the secondary somatosensory cortex (S2) of the monkey brain during acute stroke.Current research in neurobiology · 2023Article
- Task effects on functional connectivity measures after stroke.Experimental brain research · 2022Article
- Sensory and motor cortical excitability changes induced by rTMS and sensory stimulation in stroke: A randomized clinical trial.Frontiers in neuroscience · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroimaging-derived markers are used to model post-stroke impairment. Among these, lesion size, corticospinal-tract lesion-load (CST-LL) and resting-state functional-connectivity (rs-FC) have been correlated with impairment. It has been shown that the sensory cortex (S1) is associated with motor learning and is essential for post-stroke recovery; yet stroke-induced changes in S1 connectivity alone are yet to be investigated. We aim to determine whether interhemispheric rs-FC could be used to refine imaging models of stroke-related impairment. Subjects' post-stroke and age-matched controls underwent rs-fMRI. Stroke-related disability was correlated with lesion size, CST-LL and interhemispheric S1 and M1 rs-FC as independent seeds. Regression analyses were performed to assess the contribution of these markers in stroke-related deficits. Post-stroke subjects showed an asymmetrical pattern of rs-FC in which affected hemisphere S1 and M1 were mostly connected with ipsi-lesional regions. Correlations between rs-FC and stroke-severity were found. Adding rs-FC of S1 to the regression model of impairment decreased the variance 31% compared to lesion size only. After a stroke, S1 interhemispheric connectivity is decreased, with S1 only connected with ipsi-lesional regions. This asymmetry correlates with neurological and motor impairment. Furthermore, when combined with lesion anatomical measures, S1 connectivity might be an important marker in explaining stroke outcome.
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