Evidence map›Paper›PMID 30135462›Full record

ArticleScientific reports2018

Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice.

Isabella Santos de Genaro, Francine Maria de Almeida, Deborah Camargo Hizume-Kunzler, Henrique Takachi Moriya, Ronaldo Aparecido Silva, João Carlos Gonçalves Cruz, Renan Boeira Lopes, Renato Fraga Righetti, Rodolfo de Paula Vieira, Mitiko Saiki and 4 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Isabella Santos de GenaroPublic Employee of Sao Paulo Hospital (IAMSPE), Sao Paulo, Brazil.ORCID 0000-0002-0330-0418
Francine Maria de AlmeidaDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Deborah Camargo Hizume-KunzlerDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Henrique Takachi MoriyaBiomedical Engineering Laboratory, Escola Politecnica, University of Sao Paulo, Sao Paulo, Brazil.
Ronaldo Aparecido SilvaDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
João Carlos Gonçalves CruzUniversity City of Sao Paulo (UNICID), Sao Paulo, Brazil.
Renan Boeira LopesUniversity City of Sao Paulo (UNICID), Sao Paulo, Brazil.
Renato Fraga RighettiDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Rodolfo de Paula VieiraUniversidade Brasil, Post-graduation Program in Bioengenering, São Paulo, Brazil and Brazilian Institute of Teaching and Research in Pulmonary and Exercise Immunology (IBEPIPE), São José dos Campos, Brazil.ORCID 0000-0001-6379-1143
Mitiko SaikiNuclear and Energy Research Institute, IPEN-CNEN/SP, Sao Paulo, Brazil.
Milton Arruda MartinsDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Iolanda de Fátima Lopes Calvo TibérioDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Fernanda Magalhães Arantes-CostaDepartment of Medicine (LIM 20), School of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Beatriz Mangueira Saraiva-RomanholoPublic Employee of Sao Paulo Hospital (IAMSPE), Sao Paulo, Brazil. beatrizmsaraiva@gmail.com.
Universidade de São Paulo · BRUniversidade Cidade de São Paulo · BRNational Nuclear Energy Commission · BRUniversidade Brasil · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazilian Federal Agency for the Support and Evaluation of Graduate Education) 2696/2013Fundação de Amparo à Pesquisa do Estado de São Paulo (São Paulo Research Foundation) 2009/53904-9Fundação de Amparo à Pesquisa do Estado de São Paulo (São Paulo Research Foundation) 2012/15165-2
6 · The paper itself

Abstract

Work-exacerbated asthma (WEA) is defined as preexisting asthma that worsens with exposure to irritants [e.g., chlorine (Cl

Indexed as

AllergensAnimalsAsthmaBronchoalveolar Lavage FluidChlorineCytokinesDisease Models, AnimalEosinophilsInflammationLungMaleMiceMice, Inbred BALB CNasal MucosaNitric Oxide Synthase Type IIRespiratory Function TestsAllergensChlorineCytokinesNitric Oxide Synthase Type IINos2 protein, mouserho-Associated KinasesRock2 protein, mouse

Identifiers

PMID30135462
PMCPMC6105688
OpenAlexW2886662855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.