ArticleScientific reports2018
Experimental evaluation of the impact of household aerosolized insecticides on pyrethroid resistant Aedes aegypti.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 82 citations in OpenAlex.
- Insecticide susceptibility and knockdown resistance (Kdr) mutations (F1534C and V1016I) in Aedes aegypti populations from Dar es Salaam, Tanzania.Parasites & vectors · 2026Article
- Establishment and characterization of a Wolbachia (wAlbB)-infected Aedes aegypti line (Tw-Kao) for dengue control.PLoS neglected tropical diseases · 2026Article
- Insecticide resistance status and high frequency of kdr mutations in Aedes aegypti in Tegucigalpa, Honduras.Parasites & vectors · 2025Article
- Does use of domestic insecticides undermine public health control strategies?Lancet regional health. Americas · 2025Review
- Organophosphate and Pyrethroid Resistance Status of InvasiveJournal of arthropod-borne diseases · 2024Article
- Measuring insecticide resistance in a vacuum: exploring next steps to link resistance data with mosquito control efficacy.Journal of medical entomology · 2024Review
- Fine-scale monitoring of insecticide resistance in Aedes aegypti (Diptera: Culicidae) from Sri Lanka and modeling the phenotypic resistance using rational approximation.Parasites & vectors · 2024Article
- Irrigation, migration and infestation: a case study of Chagas disease vectors and bed bugs in El Pedregal, Peru.Memorias do Instituto Oswaldo Cruz · 2024Article
- Pyrethroid susceptibility reversal in Aedes aegypti: A longitudinal study in Tapachula, Mexico.PLoS neglected tropical diseases · 2024Article
- Article
- Insecticide resistance compromises the control of Aedes aegypti in Bangladesh.Pest management science · 2023Article
- Evaluation of the biological efficacy and susceptibility in Aedes aegypti to the pyrethroid insecticides deltamethrin and cyfluthrin during the Zika virus outbreak in Kuna Yala, PanamaBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Improving the efficiency of aerosolized insecticide testing against mosquitoes.Scientific reports · 2023Article
- Development of insecticide-impregnated polyester/cotton blend fabric and assessment of their repellent characteristics against Cimex lectularius and dengue vectors Aedes albopictus and Aedes aegypti.Parasites & vectors · 2023Article
- Pyrethroid genetic resistance in the dengue vector (Frontiers in public health · 2023Article
- Independent evaluation of Wolbachia infected male mosquito releases for control of Aedes aegypti in Harris County, Texas, using a Bayesian abundance estimator.PLoS neglected tropical diseases · 2022Article
- The fabrication and assessment of mosquito repellent cream for outdoor protection.Scientific reports · 2022Article
- Lab-scale characterization and semi-field trials of Wolbachia Strain wAlbB in a Taiwan Wolbachia introgressed Ae. aegypti strain.PLoS neglected tropical diseases · 2022Article
- Insecticide resistance in Aedes aegypti from Tapachula, Mexico: Spatial variation and response to historical insecticide use.PLoS neglected tropical diseases · 2021Article
- The impact of sublethal permethrin exposure on susceptible and resistant genotypes of the urban disease vector Aedes aegypti.Pest management science · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The extensive reliance on insecticides to control Aedes aegypti mosquitoes and disrupt transmission of dengue, chikungunya and Zika has fueled the emergence of widespread resistance to insecticides. Mismatch between the frequency of pyrethroid resistance in mosquitoes and the occurrence of pyrethroid-based insecticide applications for vector control is often hypothesized to be due to household use of commercial insecticide products. We experimentally quantified phenotypic and genotypic responses of four Ae. aegypti strains (three field, pyrethroid resistant, and one laboratory, pyrethroid susceptible) after exposure to two commonly used household aerosol insecticide products (a space spray and a residual spray formulation) containing pyrethroid active ingredients. Experiments were performed within homes of Mérida, Mexico. After exposure to the products, all three pyrethroid resistant field Ae. aegypti strains had significantly lower mortality rates (averaging 41% and 50% for the two products, respectively) than the controls (99%). Applying insecticides as surface sprays led to a significant increase in the frequency of I1016 kdr homozygotes in surviving Ae. aegypti, suggesting strong selection pressure for this allele. Given the large-scale use of household aerosol insecticide products in areas that are endemic for Ae. aegypti-transmitted diseases, their role as a pyrethroid resistance selection source, particularly when used as space sprays, should be taken into consideration when designing resistance management plans.
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