ReviewJournal of cardiovascular development and disease2018
The Anatomy, Development, and Evolution of the Atrioventricular Conduction Axis.
Review in Journal of cardiovascular development and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Myocardial Immune Niches in Homeostasis and Inflammation.Immunological reviews · 2026Review
- Regeneration of the lizard heart after cryoinjury.Experimental physiology · 2026Article
- The cardiac conduction system: development, function and therapeutic targets.Nature reviews. Cardiology · 2026Review
- Genetics of supraventricular tachycardia: current evidence with a focus on translational relevance and personalized medicine.Frontiers in cardiovascular medicine · 2026Review
- The Anatomy of the Atrioventricular Node.Journal of cardiovascular development and disease · 2025Review
- The Atrioventricular Node Revisited.Arrhythmia & electrophysiology review · 2025Article
- Successful Slow Pathway Modification with Radiofrequency Ablation in a Patient with AVNRT and Congenital IVC Continuity with Azygos Vein.European journal of case reports in internal medicine · 2025Article
- The Atrioventricular Conduction Axis in Man and Mouse.Journal of cardiovascular development and disease · 2024Review
- Relevance of Anatomical Significance of AV Nodal Structures within Koch's Triangle and Pyramid.Journal of cardiovascular development and disease · 2024Review
- Inferior Extensions of the Atrioventricular Node.Arrhythmia & electrophysiology review · 2021Review
- The Atrioventricular Conduction Axis and its Implications for Permanent Pacing.Arrhythmia & electrophysiology review · 2021Review
- Three-dimensional visualization of the bovine cardiac conduction system and surrounding structures compared to the arrangements in the human heart.Journal of anatomy · 2021Article
- An Appreciation of Anatomy in the Molecular World.Journal of cardiovascular development and disease · 2020Review
- Zippering Up a Role for ZO-1 in Atrioventricular Node Conduction and Disease.Circulation research · 2020Article
- Reptiles as a Model System to Study Heart Development.Cold Spring Harbor perspectives in biology · 2020Review
- Predominant Involvement of the Aortic Root in a Patient with Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis: Congestive Heart Failure due to Subacute Severe Aortic Regurgitation and Reversible Conduction Disturbance.Internal medicine (Tokyo, Japan) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is now well over 100 years since Sunao Tawara clarified the location of the axis of the specialised myocardium responsible for producing coordinated ventricular activation. Prior to that stellar publication, controversies had raged as to how many bundles crossed the place of the atrioventricular insulation as found in mammalian hearts, as well as the very existence of the bundle initially described by Wilhelm His Junior. It is, perhaps surprising that controversies continue, despite the multiple investigations that have taken place since the publication of Tawara's monograph. For example, we are still unsure as to the precise substrates for the so-called slow and fast pathways into the atrioventricular node. Much has been done, nonetheless, to characterise the molecular make-up of the specialised pathways, and to clarify their mechanisms of development. Of this work itself, a significant part has emanated from the laboratory coordinated for a quarter of a century by Antoon FM Moorman. In this review, which joins the others in recognising the value of his contributions and collaborations, we review our current understanding of the anatomy, development, and evolution of the atrioventricular conduction axis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.