Evidence map›Paper›PMID 30135229›Full record

ArticleJournal of clinical microbiology2018

Usefulness of Automated Latex Turbidimetric Rapid Plasma Reagin Test for Diagnosis and Evaluation of Treatment Response in Syphilis in Comparison with Manual Card Test: a Prospective Cohort Study.

Motoyuki Tsuboi, Takeshi Nishijima, Takahiro Aoki, Katsuji Teruya, Yoshimi Kikuchi, Hiroyuki Gatanaga, Shinichi Oka

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Motoyuki TsuboiAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Takeshi NishijimaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan tnishiji@acc.ncgm.go.jp.
Takahiro AokiAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Katsuji TeruyaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Yoshimi KikuchiAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Hiroyuki GatanagaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Shinichi OkaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
National Center for Global Health and Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The usefulness of an automated latex turbidimetric rapid plasma reagin (RPR) assay, compared to the conventional manual card test (serial 2-fold dilution method), for the diagnosis of syphilis and evaluation of treatment response remains unknown. We conducted (i) a cross-sectional study and (ii) a prospective cohort study to elucidate the correlation between automated and manual tests and whether a 4-fold decrement is a feasible criterion for successful treatment with the automated test, respectively, in HIV-infected patients, from October 2015 to November 2017. Study i included 518 patients. The results showed strong correlation between the two tests (

Indexed as

AdultAIDS-Related Opportunistic InfectionsAnti-Bacterial AgentsAntibodies, BacterialAutomation, LaboratoryCross-Sectional StudiesDrug MonitoringFemaleHumansMaleMiddle AgedProspective StudiesReagent Kits, DiagnosticReaginsSyphilisSyphilis SerodiagnosisAnti-Bacterial AgentsAntibodies, BacterialReagent Kits, DiagnosticReaginsautomated testmanualrapid plasma reaginsyphilistreatment response

Identifiers

PMID30135229
PMCPMC6204675
OpenAlexW2888586291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.