Evidence map›Paper›PMID 30134844›Full record

ArticleBMC infectious diseases2018

Molecular characterization and epidemiology of carbapenem non-susceptible Enterobacteriaceae isolated from the Eastern region of Heilongjiang Province, China.

Xue Gong, Jisheng Zhang, Shanshan Su, Yanjun Fu, Mingjia Bao, Yong Wang, Xiaoli Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Transcriptomic correlates of ceftazidime-avibactam collateral sensitivity in tigecycline-resistant NDM-producing enterobacter cloacae complex.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Article
  4. Insertion sequences inFrontiers in microbiology · 2025
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  5. In vitro and in vivo activity of ceftazidime/avibactam and aztreonam alone or in combination against mcr-9, serine- and metallo-β-lactamases-co-producing carbapenem-resistant Enterobacter cloacae complex.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  6. Article
  7. Article
  8. Increased Expression and Amplification ofMicrobiology spectrum · 2022
    Article
  9. Molecular Epidemiology of Carbapenem-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  10. Article
  11. Molecular characterization of NDM-1-producing carbapenem-resistantFrontiers in cellular and infection microbiology · 2022
    Article
  12. Article
  13. Article
  14. Molecular Characterization of Carbapenemase-ProducingInfection and drug resistance · 2021
    Article
  15. An Outbreak of Carbapenem-ResistantFrontiers in cellular and infection microbiology · 2021
    Article
  16. Article
  17. Carbapenemase Production and Epidemiological Characteristics of Carbapenem-ResistantFrontiers in cellular and infection microbiology · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue GongDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Jisheng ZhangDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Shanshan SuDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Yanjun FuDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China.
Mingjia BaoCenter for Disease Control and Prevention, Jiamusi, Heilongjiang, China.
Yong WangDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China. 15331878255@163.com.
Xiaoli ZhangDepartment of Microbiology, the First Affiliated Hospital of Jiamusi University, Jiamusi, Heilongjiang, China. jmszxl123@163.com.ORCID http://orcid.org/0000-0001-7854-0515
First Affiliated Hospital of Jiamusi University · CNJiamusi University · CN

Funding

Heilongjiang Provincial Health and Family Planning Commission on Scientific Research Project 2017-405Natural Science Foundation of Heilongjiang Province D201224
6 · The paper itself

Abstract

backgroundThe aim of this study was to elucidate the molecular epidemiology of carbapenem non-susceptible Enterobacteriaceae(CNSE) isolated in the Eastern region of Heilongjiang Province, China, and the mechanism of carbapenem resistance.

methodsA total of 53 CNSE isolates were collected in a grade-3 hospital in Heilongjiang province. Sensitivity to antibiotics was determined using the VITEK-2 Compact automatic system. The modified Hodge test (MHT) and modified carbapenem inactivation test (mCIM) were performed for phenotypic identification. Beta-lactamases gene were detected by Polymerase chain reaction(PCR) and DNA sequencing. The transfer of bla

resultsCNSE were highly resistant to the majority of antimicrobial agents. The resistance rate was 100% for first, third, fourth generation cephalosporins and enzyme inhibitor compounds. Gentamicin and tobramycin recorded a resistance rate higher than 80%. Less than 30% resistance was detected for amikacin and levofloxacin. Among CNSE 52(98.1%) and 48(90.6%) of CNSE were positive for mCIM and MHT respectively. There were 42 positive bla

conclusionThe carbapenem resistance phenomenon is alarming and bla

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial Agentsbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCarbapenemsChildChild, PreschoolChinaDisease OutbreaksDrug Resistance, Multiple, BacterialEnterobacteriaceae InfectionsFemaleHumansAnti-Bacterial Agentsbeta-LactamasesCarbapenemsCarbapenem non-susceptible EnterobacteriaceaeEpidemiologic typingMolecular characterization

Identifiers

PMID30134844
PMCPMC6106938
OpenAlexW2888738378

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.