ArticleBMC microbiology2018
The microbiota in the intestinal and respiratory tracts of naked mole-rats revealed by high-throughput sequencing.
Article in BMC microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Characterisation of bacteria-induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease.The Journal of pathology · 2026Article
- Impact of acute and chronic hypoxia on the heme oxygenase/carbon monoxide pathway in naked mole-rats (Heterocephalus glaber).The Journal of experimental biology · 2025Article
- Different active exogenous carbons improve the yield and quality of roses by shaping different bacterial communities.Frontiers in microbiology · 2025Article
- Gut microbiota and healthy longevity.Science China. Life sciences · 2024Review
- What Can the Gut Microbiota of Animals Teach Us about the Relationship between Nutrition and Burden of Lifestyle Diseases?Nutrients · 2024Review
- Bacterial microbiome of faecal samples of naked mole-rat collected from the toilet chamber.BMC research notes · 2022Article
- Gut Microbiome Alterations and Hepatic Metabolic Flexibility in the Gansu Zokor,Frontiers in cardiovascular medicine · 2022Article
- Composition of gut and oropharynx bacterial communities in Rattus norvegicus and Suncus murinus in China.BMC veterinary research · 2020Article
- The use of non-traditional models in the study of cancer resistance-the case of the naked mole rat.Oncogene · 2020Review
- Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe naked mole-rat (NMR, Heterocephalus glaber) is being bred as a novel laboratory animal due to its unique biological characteristics, including longevity, cancer resistance, hypoxia tolerance, and pain insensitivity. It is expected that differences exist between the microbiota of wild NMRs and that of NMRs in an artificial environment. Overall, the effect of environment on changes in the NMR microbiota remains unknown. In an attempt to understand the microbiota composition of NMRs in captivity, variability in the microbiota of the intestinal and respiratory tracts of two groups of NMRs was assessed under two conditions.
resultsThe results obtained by high-throughput sequencing revealed significant differences at the phylum, class, order, family and genus levels in the microbiota between the two groups of NMRs examined (first group in conventional environment, second group in barrier environment). For the trachea, 24 phyla and 533 genera and 26 phyla and 733 genera were identified for the first and second groups of animals. Regarding the cecum, 23 phyla and 385 genera and 25 phyla and 110 genera were identified in the microbiota of first and second groups of animals. There were no obvious differences between females and males or young and adult animals.
conclusionsOur results suggest that the intestinal and respiratory tract NMR microbiota changed during captivity, which may be related to the transition to the breeding environment. Such changes in the microbiota of NMRs may have an effect on the original characteristics, which may be the direction of further research studies.
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