Evidence map›Paper›PMID 30134564›Full record

ReviewNanomaterials (Basel, Switzerland)2018

Trends towards Biomimicry in Theranostics.

Michael Evangelopoulos, Alessandro Parodi, Jonathan O Martinez, Ennio Tasciotti

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. New anti-cancer explorations based on metal ions.Journal of nanobiotechnology · 2022
    Review
  6. Review
  7. Review
  8. Humanized Biomimetic Nanovesicles for Neuron Targeting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael EvangelopoulosCenter for Biomimetic Medicine, Houston Methodist Research Institute, Houston, TX 77030, USA. mevangelopoulos@houstonmethodist.org.ORCID 0000-0002-5300-4289
Alessandro ParodiDepartment of Pharmacology, University of Illinois at Chicago, Chicago, IL 60607, USA. aparodi@uic.edu.
Jonathan O MartinezCenter for Biomimetic Medicine, Houston Methodist Research Institute, Houston, TX 77030, USA. jomartinez@houstonmethodist.org.ORCID 0000-0002-0517-366X
Ennio TasciottiCenter for Biomimetic Medicine, Houston Methodist Research Institute, Houston, TX 77030, USA. etasciotti@houstonmethodist.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the years, imaging and therapeutic modalities have seen considerable progress as a result of advances in nanotechnology. Theranostics, or the marrying of diagnostics and therapy, has increasingly been employing nano-based approaches to treat cancer. While first-generation nanoparticles offered considerable promise in the imaging and treatment of cancer, toxicity and non-specific distribution hindered their true potential. More recently, multistage nanovectors have been strategically designed to shield and carry a payload to its intended site. However, detection by the immune system and sequestration by filtration organs (i.e., liver and spleen) remains a major obstacle. In an effort to circumvent these biological barriers, recent trends have taken inspiration from biology. These bioinspired approaches often involve the use of biologically-derived cellular components in the design and fabrication of biomimetic nanoparticles. In this review, we provide insight into early nanoparticles and how they have steadily evolved to include bioinspired approaches to increase their theranostic potential.

Indexed as

bioinspiredbiomimeticcancermultistage nanovectorsnanomedicinenanoparticlestheranostics

Identifiers

PMID30134564
PMCPMC6164646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.