ReviewChildren (Basel, Switzerland)2018
Depression in Children and Adolescents with Autism Spectrum Disorder.
Review in Children (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 2 syntheses or guidelines pooled it, 130 citations in OpenAlex.
- Systematic review and meta-analysis: multimodal functional and anatomical neural alterations in autism spectrum disorder.Molecular autism · 2024Pooled it
- Predictors of Health-Related Quality of Life in Neurodivergent Children: A Systematic Review.Clinical child and family psychology review · 2024Pooled it
- Depressive Symptoms in Autistic Youth with Anxiety Disorders.Journal of developmental and behavioral pediatrics : JDBP · 2023Trial
- Co-Designing a Digital Coach-Supported Parenting Program for Internalising Problems in Autistic Children.European journal of investigation in health, psychology and education · 2026Article
- Depression in Autism Spectrum Disorder: Neurobiological Convergence and Emerging Therapeutic Strategies.Biology · 2026Review
- Suicide prevention interventions and supports for the Autistic community: a scoping review protocol.BMJ open · 2026Article
- Clinical Correlates of Major Depression in Psychiatrically Referred Youth With and Without Autism: A Controlled Study.Journal of autism and developmental disorders · 2026Article
- Article
- Sleep problems in autistic children and adolescents: an age-stratified approach.Frontiers in psychology · 2026Article
- From risk to resilience: a narrative overview of modifiable factors influencing depression in children with autism spectrum disorder (part I).Frontiers in psychiatry · 2026Review
- Insomnia severity and its association with gaming behavior and perceived health in autistic adults.BMC psychology · 2025Article
- Study protocol for a multimethod investigation of the development of social and nonsocial reward responsivity and depression in autistic adolescents: Reward and Depression in Autism (RDA).BMC psychology · 2025Article
- Predicting Self-Esteem and Depressive Symptoms from Social Skills Among Youth Referred for an Autism Evaluation.Child psychiatry and human development · 2025Article
- Patterns in Medication Use for Treatment of Depression in Autistic Spectrum Disorder.Journal of autism and developmental disorders · 2025Article
- Psychiatric Comorbidities in Autistic Adolescents Without Intellectual Impairment: A Focus on Parent- and Self-Reported Psychopathological Assessment.Brain sciences · 2025Article
- Efficacy and Safety of Neuromodulation Interventions for Autism Spectrum Disorders with Comorbidities: A Systematic Review.Neuropsychiatric disease and treatment · 2025Review
- Exploring co-occurring conditions in Iraqi children with autism spectrum disorder: prevalence, characteristics, and potential risk factors.Frontiers in psychiatry · 2025Article
- Article
- Sex differences in the prevalence of common comorbidities in autism: a narrative review.Ewha medical journal · 2025Review
- Prevalence, Symptom Profiles, and Correlates of Mixed Anxiety-Depression in Male and Female Autistic Youth.NeuroSci · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism spectrum disorder (ASD) has a high rate of psychiatric comorbidity. The prevalence of comorbid depression seems to correlate with higher functioning forms of ASD and increasing age. Adolescence is a time when youth struggle with identity and interpersonal relationships, and a diagnosis of ASD further complicates this process. Adolescents with ASD may be more aware of the social communication deficits that come with the diagnosis than children with ASD, and it is theorized that higher functioning adolescents may experience this more acutely. While this may be true, the lack of reliable rating and diagnostic scales for depression in individuals with ASD makes it difficult to accurately measure rates of depression among individuals with more severe verbal deficits. While some research has focused on the prevalence of comorbid depression in children and adolescents with ASD and on the associated risk factors, there is very little evidence guiding treatment, including no empirical studies on psychopharmacology for depression in this population. Available evidence exists only in psychosocial approaches to treatment at this time and is mostly limited to adult studies. Current evidence will be presented in this review, including prevalence rates of depression in youth with ASD, various risk and protective factors, the use of diagnostic rating scales, and treatment studies. The lack of evidence supporting various treatment approaches will be highlighted, including challenges specific to the treatment of depression in ASD, which are not addressed in the current treatment studies in typically developing youth with depression.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.