ArticleJournal of clinical medicine2018
Perioperative Cumulative Fluid Balance and Its Association with an Increase in Costs after Major Surgery.
Article in Journal of clinical medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Non-invasive goal-directed fluid therapy with the pleth variability index (PVI): a systematic review and meta-analysis.Journal of clinical monitoring and computing · 2025Pooled it
- Terms, Definitions, Nomenclature, and Routes of Fluid Administration.Frontiers in veterinary science · 2020Pooled it
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Positive fluid balance (FB) during the perioperative period may increase the incidence of postoperative complications, which may lead to longer hospitalization and higher hospital costs. However, a definitive association between positive FB and hospital costs has not yet been established. This retrospective observational study examined the association between perioperative FB and hospital costs of patients who underwent major surgical procedures. Medical records of patients who underwent major surgery (surgery time >2 h, estimated blood loss >500 mL) from January 2010 to December 2017 were analyzed to determine the associations between calculated FB (%, total input fluid-output fluid in liter/weight (kg) at admission) and total hospital cost ($). The analysis included medical data of 7010 patients. Multivariable linear regression analyses showed that a 1% increase in FB in postoperative day (POD) 0 (24 h), 0⁻1 (48 h), 0⁻2 (72 h), and 0⁻3 (96 h) significantly increased the total cost by $967.8 (95% confidence interval [CI]: 803.4⁻1132.1), $688.8 (95% CI: 566.3⁻811.2), $591 (95% CI: 485.7⁻696.4), and $434.2 (95% CI: 349.4⁻519.1), respectively (all
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