Evidence map›Paper›PMID 30134200›Full record

ArticleImmunity2018

Dangerously Fit: Extracellular ATP Aids Memory T Cell Metabolism.

Trever T Greene, Lara Labarta-Bajo, Elina I Zuñiga

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Trever T GreeneDivision of Biological Sciences, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Lara Labarta-BajoDivision of Biological Sciences, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Elina I ZuñigaDivision of Biological Sciences, University of California San Diego, La Jolla, San Diego, CA 92093, USA. Electronic address: eizuniga@ucsd.edu.
University of California San Diego · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a recent issue of Nature, Borges da Silva et al. (2018) reveal that P2RX7, a receptor for extracellular ATP, promotes CD8 T cell memory by enhancing metabolic fitness. This work links an ancient "danger" signal with long-term immunity.

Indexed as

Receptors, PurinergicT-LymphocytesAdenosine TriphosphateCD8-Positive T-LymphocytesImmunityAdenosine TriphosphateReceptors, Purinergic

Identifiers

PMID30134200
OpenAlexW2888425252

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.