Evidence map›Paper›PMID 30134043›Full record

ArticleJournal of cellular and molecular medicine2018

Deletion of caveolin-1 attenuates LPS/GalN-induced acute liver injury in mice.

Tsung-Huang Tsai, Kabik Tam, Shu-Fen Chen, Jun-Yang Liou, Yi-Chen Tsai, Yen-Ming Lee, Tai-Yu Huang, Song-Kun Shyue

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Article
  10. Article
  11. Role of Caveolin-1 in Sepsis - A Mini-Review.Frontiers in immunology · 2022
    Review
  12. Article
  13. Article
  14. Article
  15. Protective Role ofFrontiers in pharmacology · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Edible InsectNutrients · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Tsung-Huang TsaiInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Kabik TamInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Shu-Fen ChenInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Jun-Yang LiouInstitute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan.
Yi-Chen TsaiInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yen-Ming LeeInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Tai-Yu HuangInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Song-Kun ShyueInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.ORCID 0000-0002-1057-8696
Institute of Biomedical Sciences, Academia Sinica · TWNational Health Research Institutes · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute hepatic injury caused by inflammatory liver disease is associated with high mortality. This study examined the role of caveolin-1 (Cav-1) in lipopolysaccharide (LPS) and D-galactosamine (GalN)-induced fulminant hepatic injury in wild type and Cav-1-null (Cav-1

Indexed as

AnimalsApoptosisCaveolin 1Chemical and Drug Induced Liver InjuryHepatocytesHumansInflammationIntercellular Adhesion Molecule-1Kupffer CellsLipopolysaccharide ReceptorsLipopolysaccharidesLiverMiceNeutrophil InfiltrationNF-kappa BNitric Oxide Synthase Type IICaveolin 1Cd14 protein, mouseIntercellular Adhesion Molecule-1Lipopolysaccharide ReceptorsLipopolysaccharidesNF-kappa BNitric Oxide Synthase Type IIRELA protein, humanTlr4 protein, mouseToll-Like Receptor 4Transcription Factor RelAacute liver injurycaveolin-1D-galactosaminelipopolysaccharidetoll-like receptor 4

Identifiers

PMID30134043
PMCPMC6201225
OpenAlexW2888112019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.