Evidence map›Paper›PMID 30133309›Full record

ArticleCancer biotherapy & radiopharmaceuticals2018

Biodistribution and Internal Radiation Dosimetry of

Yoo Sung Song, Joong Hyun Kim, Byung Chul Lee, Jae Ho Jung, Hyun Soo Park, Sang Eun Kim

Abstract read
In one paragraph

Article in Cancer biotherapy & radiopharmaceuticals, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Experimental evaluation of absolute quantification inJournal of applied clinical medical physics · 2022
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yoo Sung Song1 Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seongnam, Republic of Korea.
Joong Hyun Kim2 Division of Chemical and Medical Metrology, Center for Ionizing Radiation, Korea Research Institute of Standards and Science , Daejeon, Republic of Korea.
Byung Chul Lee1 Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seongnam, Republic of Korea.
Jae Ho Jung1 Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seongnam, Republic of Korea.
Hyun Soo Park1 Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seongnam, Republic of Korea.
Sang Eun Kim1 Department of Nuclear Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine , Seongnam, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntegrin α MATERIALS AND

methodsSix healthy volunteers underwent whole-body simultaneous anterior and posterior scans, preceded by transmission scans using cobalt-57 flood source, with a dual head gamma camera system, at 0, 1, 2, 4, 8, and 24 h postinjection of

resultsHigh radiation doses of renal and biliary excretion tracks such as the urinary bladder wall, upper large intestine, kidneys, liver, and gallbladder wall (19.15 ± 6.84, 19.28 ± 4.78, 15.67 ± 0.90, 9.13 ± 1.71, and 9.09 ± 2.03 μGy/MBq, respectively) were observed. The ED and effective dose equivalent were 5.08 ± 0.53 and 7.11 ± 0.58 μSv/MBq, respectively.

conclusionsDosimetry results were comparable to other radiolabeled peptides and were considered safe and efficient for clinical usage.

Indexed as

AgedFemaleHumansIntegrin alphaVbeta3MaleMiddle AgedNeovascularization, PathologicOrganotechnetium CompoundsRadiometryRadiopharmaceuticalsTissue DistributionTomography, Emission-Computed, Single-PhotonIntegrin alphaVbeta3Organotechnetium CompoundsRadiopharmaceuticals99mTc-IDA-D-[c(RGDfK)]2angiogenesisbiodistributiondosimetryintegrin αvβ3 expression

Identifiers

PMID30133309
PMCPMC6241326

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.