Evidence map›Paper›PMID 30133173›Full record

Observational studyArthritis care & research2019

Knee Osteoarthritis and the Risk of Medically Treated Injurious Falls Among Older Adults: A Community-Based US Cohort Study.

Kamil E Barbour, Naoko Sagawa, Robert M Boudreau, Mary E Winger, Jane A Cauley, Michael C Nevitt, Tomoko Fujii, Kushang V Patel, Elsa S Strotmeyer

Open access · greenAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Arthritis care & research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Comparative outcome analyses of stromal vascular fractionWorld journal of experimental medicine · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Analysis of the Associations between Arthritis and Fall Histories in Korean Adults.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Kamil E BarbourCenters for Disease Control and Prevention, Atlanta, Georgia, and United States Public Health Service, Commissioned Corps, Rockville, Maryland.
Naoko SagawaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Robert M BoudreauUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Mary E WingerUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Jane A CauleyUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Michael C NevittUniversity of California, San Francisco.
Tomoko FujiiUniversity of Pittsburgh, Pittsburgh, Pennsylvania, and The University of Tokyo Hospital, Tokyo, Japan.
Kushang V PatelUniversity of Washington, Seattle.
Elsa S StrotmeyerUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USCenters for Disease Control and Prevention · USSeattle University · USUniversity of California, San Francisco · USUniversity of Tokyo Hospital · JP

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
TRAINING IN THE EPIDEMIOLOGY OF AGINGT32AG000181 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 1989 to 2025
$6.2M
Peripheral Nerve Function Decline in an Aged CohortR01AG028050 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STROTMEYER, ELSA S. · 2007 to 2015
$3.5M
End of Life in the Very OldR01NR012459 · NINR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ALBERT, STEVEN M, LUNNEY, JUNE R · 2011 to 2015
$2.7M
DYNAMICS OF HEALTH .AGING . AND BODY COMPOSITION /Pittsburgh/-260962101N01AG062101 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 1996 to 2004
$996k
DYNAMICS OF HEALTH . AGING . AND BODY COMPOSITION /Memphis/-26062103N01AG062103 · NIA · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · 1996 to 2004
$793k
HEALTH ABC--COORDINATING UNIT /California/-260062106N01AG062106 · NIA · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · 1996 to 2004
$109k
Intramural CDC HHS CC999999NIA NIH HHS N01 AG062101NIA NIH HHS N01 AG062103NIA NIH HHS N01 AG062106NIA NIH HHS P30 AG024827NIA NIH HHS R01 AG028050NIA NIH HHS T32 AG000181NIH (Intramural Research Program)NINR NIH HHS R01 NR012459
6 · The paper itself

Abstract

objectiveThe risk of falls among adults with knee osteoarthritis (OA) has been documented, yet, to our knowledge no studies have examined knee OA and the risk of medically treated injurious falls (overall and by sex), which is an outcome of substantial clinical and public health relevance.

methodsUsing data from the Health Aging and Body Composition Knee Osteoarthritis Substudy, a community-based study of white and African American older adults, we tested associations between knee OA status and the risk of injurious falls among 734 participants with a mean ± SD age of 74.7 ± 2.9 years. Knee radiographic OA (ROA) was defined as having a Kellgren-Lawrence grade of ≥2 in at least 1 knee. Knee symptomatic ROA (sROA) was defined as having both ROA and pain symptoms in the same knee. Injurious falls were defined using a validated diagnosis code algorithm from linked Medicare fee-for-service claims. Cox regression modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs).

resultsThe mean ± SD follow-up time was 6.59 ± 3.12 years. Of the 734 participants, 255 (34.7%) had an incident injurious fall over the entire study period. In the multivariate model, compared with those without ROA or pain, individuals with sROA (HR 1.09 [95% CI 0.73-1.65]) did not have a significantly increased risk of injurious falls. Compared with men without ROA or pain, men with sROA (HR 2.57 [95% CI 1.12-5.91]) had a significantly higher risk of injurious falls. No associations were found for women or by injurious fall type.

conclusionKnee sROA was independently associated with an increased risk of injurious falls in older men, but not in older women.

Indexed as

Accidental FallsAgedFemaleHumansKnee JointMaleOsteoarthritis, KneePennsylvaniaPrevalencePrognosisRisk AssessmentRisk FactorsSex FactorsTennesseeTime Factors

Identifiers

PMID30133173
PMCPMC6384154
OpenAlexW2888365420

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.