Evidence map›Paper›PMID 30133157›Full record

ArticleJournal of cellular and molecular medicine2018

Reduction of PINK1 or DJ-1 impair mitochondrial motility in neurites and alter ER-mitochondria contacts.

Cristina Parrado-Fernández, Bernadette Schneider, Maria Ankarcrona, Melissa M Conti, Mark R Cookson, Miia Kivipelto, Ángel Cedazo-Mínguez, Anna Sandebring-Matton

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  7. Review
  8. Genome-wide kinase-MAM interactome screening reveals the role of CK2A1 in MAM CaProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Review
  10. Ratiometric measurement of MAM CaNature communications · 2023
    Article
  11. Review
  12. Reduced ER-mitochondrial contact sites and mitochondrial CaFrontiers in cell and developmental biology · 2023
    Article
  13. Article
  14. Review
  15. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Cristina Parrado-FernándezDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-2771-3206
Bernadette SchneiderDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.
Maria AnkarcronaDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.
Melissa M ContiLaboratory of Neurogenetics, National Institute on Aging/NIH, Bethesda, Maryland.
Mark R CooksonLaboratory of Neurogenetics, National Institute on Aging/NIH, Bethesda, Maryland.
Miia KivipeltoDivision of Clinical Geriatrics, Center for Alzheimer Research, NVS, Karolinska Institutet, Stockholm, Sweden.
Ángel Cedazo-MínguezDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.
Anna Sandebring-MattonDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-7819-0495
Karolinska Institutet · SENational Institute on Aging · USStockholm University · SE

Funding

Recessive parkinsonism and mitochondrial functionZIAAG000940 · NIA · NATIONAL INSTITUTE ON AGING · PI COOKSON, MARK · 2009 to 2019
$3.0M
6 · The paper itself

Abstract

Subcellular distribution of mitochondria in neurons is crucial for meeting the energetic demands, as well as the necessity to buffer Ca

Indexed as

AxonsCalciumCell LineCell MovementDendritesDopaminergic NeuronsDynaminsGene Knockdown TechniquesGlycogen Synthase Kinase 3 betaGTP PhosphohydrolasesHumansMicroscopy, ElectronMicrotubule-Associated ProteinsMitochondriaMitochondrial ProteinsNeuritesCalciumDNM1L protein, humanDynaminsGlycogen Synthase Kinase 3 betaGTP PhosphohydrolasesMicrotubule-Associated ProteinsMitochondrial ProteinsPARK7 protein, humanProtein Deglycase DJ-1Protein KinasesPTEN-Induced Putative KinaseER-mitochondrial contactsmitochondrial motilityParkinsonismPINK1

Identifiers

PMID30133157
PMCPMC6201361
OpenAlexW2888524862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.