Evidence map›Paper›PMID 30133119›Full record

ArticleJournal of cellular and molecular medicine2018

CCR6 controls autoimmune but not innate immunity-driven experimental arthritis.

Michael Bonelli, Antonia Puchner, Lisa Göschl, Silvia Hayer, Birgit Niederreiter, Guenter Steiner, Katharina Tillmann, Roberto Plasenzotti, Bruno Podesser, Philippe Georgel and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Michael BonelliInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-6122-7482
Antonia PuchnerInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Lisa GöschlInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Silvia HayerInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Birgit NiederreiterInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Guenter SteinerInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-5089-7405
Katharina TillmannDivision of Biomedical Research, Medical University of Vienna, Vienna, Austria.
Roberto PlasenzottiDivision of Biomedical Research, Medical University of Vienna, Vienna, Austria.
Bruno PodesserDivision of Biomedical Research, Medical University of Vienna, Vienna, Austria.
Philippe GeorgelNSERM UMR_S 1109, Université de Strasbourg, France.
Josef SmolenInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Clemens ScheineckerInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Stephan BlümlInternal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATUniversité de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, characterized by synovial infiltration of various inflammatory cells. Chemokines are involved in controlling the recruitment of different cell types into the synovial membrane. The role of CCR6 in the development of arthritis so far remains unclear. In this study, we investigated the role of CCR6 in the pathogenesis of arthritis using three different murine arthritis models. Compared to WT animals, CCR6

Indexed as

AnimalsArthritis, ExperimentalArthritis, RheumatoidAutoimmune DiseasesChemokine CCL20HumansImmunity, InnateMiceReceptors, CCR6Synovial MembraneCCL20 protein, mouseCCR6 protein, mouseChemokine CCL20Receptors, CCR6adaptive immune systemarthritisCCR6chemokine receptorsCIAinnate immune systemrheumatoid arthritis

Identifiers

PMID30133119
PMCPMC6201376
OpenAlexW2888175247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.