Evidence map›Paper›PMID 30132841›Full record

ArticleJournal of cellular physiology2018

Peroxidase expression is decreased by palmitate in cultured podocytes but increased in podocytes of advanced diabetic nephropathy.

Eugene Lee, Hyun Soon Lee

Open access · hybridAbstract read
In one paragraph

Article in Journal of cellular physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Research advance in the mechanism for oxidative stress-induced podocyte injury in diabetic kidney disease.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  5. Article
  6. Article
  7. The emerging role of dyslipidemia in diabetic microvascular complications.Current opinion in endocrinology, diabetes, and obesity · 2020
    Review
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eugene LeeRenal Pathology Lab, Hankook Kidney and Diabetes Institute, Seoul, Korea.
Hyun Soon LeeRenal Pathology Lab, Hankook Kidney and Diabetes Institute, Seoul, Korea.ORCID 0000-0003-0682-3115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High levels of serum free fatty acids (FFAs) are associated with lipotoxicity and type 2 diabetes. Palmitic acid (PA) is the predominant circulating saturated FFA. PA induces mitochondrial superoxide and hydrogen peroxide (H

Indexed as

AntioxidantsApoptosisCatalaseCells, CulturedDiabetes Mellitus, Type 2Diabetic NephropathiesFatty Acids, NonesterifiedGlutathione PeroxidaseGlutathione Peroxidase GPX1Homeodomain ProteinsHumansHydrogen PeroxideOxidative StressPalmitic AcidPeroxiredoxinsPodocytesAntioxidantsCatalaseFatty Acids, NonesterifiedGlutathione PeroxidaseGlutathione Peroxidase GPX1GPX1 protein, humanHomeodomain ProteinsHydrogen PeroxidePalmitic AcidPeroxiredoxinsPRRX1 protein, humanPRRX2 protein, humanSuperoxidesTGFB1 protein, humanTransforming Growth Factor beta1diabetic nephropathyfree fatty acidsH2O2peroxidasepodocytes

Identifiers

PMID30132841
PMCPMC6686159
OpenAlexW2888444279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.