Evidence map›Paper›PMID 30132549›Full record

ArticleMolecular medicine reports2018

Identification of protein complexes associated with myocardial infarction using a bioinformatics approach.

Nianhui Jiao, Yongjie Qi, Changli Lv, Hongjun Li, Fengyong Yang

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nianhui JiaoIntensive Care Unit, Laiwu People's Hospital, Laiwu, Shandong 271199, P.R. China.
Yongjie QiIntensive Care Unit, Laiwu People's Hospital, Laiwu, Shandong 271199, P.R. China.
Changli LvEmergency Department, Laiwu People's Hospital, Laiwu, Shandong 271199, P.R. China.
Hongjun LiEmergency Department, The Central Hospital of Tai'an, Tai'an, Shandong 271000, P.R. China.
Fengyong YangIntensive Care Unit, Laiwu People's Hospital, Laiwu, Shandong 271199, P.R. China.
Jinan City People's Hospital · CNShandong First Medical University · CNTaian City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is a leading cause of mortality and disability worldwide. Determination of the molecular mechanisms underlying the disease is crucial for identifying possible therapeutic targets and designing effective treatments. On the basis that MI may be caused by dysfunctional protein complexes rather than single genes, the present study aimed to use a bioinformatics approach to identifying complexes that may serve important roles in the development of MI. By investigating the proteins involved in these identified complexes, numerous proteins have been reported that are related to MI, whereas other proteins interacted with MI‑related proteins, which implied that these protein complexes may indeed be related to the development of MI. The protein complexes detected in the present study may aid in our understanding of the molecular mechanisms that underlie MI pathogenesis.

Indexed as

Protein Interaction MapsGenomicsHumansMyocardial InfarctionProteinsProteomicsRecurrenceProteins

Identifiers

PMID30132549
PMCPMC6131540
OpenAlexW2888323518

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.