Evidence map›Paper›PMID 30132433›Full record

ArticleThe British journal of nutrition2018

Sources and pattern of protein intake and risk of overweight or obesity in young UK twins.

Laura Pimpin, Susan A Jebb, Laura Johnson, Clare Llewellyn, Gina L Ambrosini

Open access · bronzeAbstract readTwin Study
In one paragraph

Article in The British journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. A Critical Review of Statistical Methods for Twin Studies Relating Exposure to Early Life Health Conditions.International journal of environmental research and public health · 2021
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Laura Pimpin1Diet and Obesity Research,Medical Research Council Human Nutrition Research,120 Fulbourn Road,Cambridge CB1 9NL,UK.
Susan A Jebb1Diet and Obesity Research,Medical Research Council Human Nutrition Research,120 Fulbourn Road,Cambridge CB1 9NL,UK.
Laura Johnson3Centre for Exercise,Nutrition and Health Sciences,School for Policy Studies,University of Bristol,8 Priory Road,Bristol BS8 1TZ,UK.
Clare Llewellyn4Department of Epidemiology and Public Health,Cancer Research UK Health Behaviour Research Centre,University College London, 119 Torrington Place,London WC1E 7HB,UK.
Gina L Ambrosini1Diet and Obesity Research,Medical Research Council Human Nutrition Research,120 Fulbourn Road,Cambridge CB1 9NL,UK.
Medical Research Council · GBMRC Human Nutrition Research · GBUniversity College London · GBUniversity of Bristol · GB

Funding

Cancer Research UK A7974Department of Health OXFCLAHRC-2014-1Medical Research Council MC_U105960389
6 · The paper itself

Abstract

High protein intake in young children is associated with excess gains in weight and body fat, but the specific role of different protein sources has yet to be described. The study aimed to investigate the role of different types of protein in the post-weaning stage on weight, BMI and overweight/obesity at 60 months. Intakes of animal, dairy and plant protein and a dietary pattern characterising variation in protein types at 21 months of age were estimated using a 3-d diet diary in a cohort of 2154 twins; weight and height were recorded every 3 months from birth to 60 months. Longitudinal mixed-effect models investigated the associations between sources of protein intake or dietary pattern scores and BMI, weight and overweight/obesity from 21 months up to 60 months. Adjusting for confounders, dairy protein intake at 21 months was positively associated with greater weight (46 (95 % CI 21, 71) g and BMI up to 60 months (0·04 (95 % CI 0·004, 0·070) kg/m2) and the odds of overweight/obesity at 3 years (OR 1·12; 95 % CI 1·00, 1·24). Milk showed associations of similar magnitude. A dietary pattern low in dairy protein and high in plant protein was associated with lower weight gain up to 60 months, but not overweight/obesity. Intake of dairy products in early childhood is most strongly associated with weight gain, compared with other protein sources. A dietary pattern characterised by lower protein intake and greater protein source diversity at 2 years may confer a lower risk of excess weight gain.

Indexed as

Body Mass IndexDietFeeding BehaviorPediatric ObesityTwinsWeight GainBody WeightChild BehaviorChild Nutritional Physiological PhenomenaChild, PreschoolDietary ProteinsEnergy IntakeFemaleHumansInfantInfant, NewbornDietary ProteinsMilk ProteinsPlant ProteinsBMIChildrenDairy protein%E proportion of total energyRRR reduced rank regressionWeight

Identifiers

PMID30132433
PMCPMC6151263
OpenAlexW2888000881

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.