Evidence map›Paper›PMID 30132026›Full record

Observational studyMedizinische Klinik, Intensivmedizin und Notfallmedizin2019

qSOFA score not predictive of in-hospital mortality in emergency patients with decompensated liver cirrhosis.

M Müller, J C Schefold, A B Leichtle, D Srivastava, G Lindner, A K Exadaktylos, C A Pfortmueller

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

M MüllerDepartment of Emergency Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
J C SchefoldDepartment of Intensive Care, Inselspital, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland.
A B LeichtleDepartment of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
D SrivastavaDepartment of Emergency Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
G LindnerDepartment of Emergency Medicine and General Internal Medicine, Hirslandenklinik am Park, Zurich, Switzerland.
A K ExadaktylosDepartment of Emergency Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
C A PfortmuellerDepartment of Intensive Care, Inselspital, Bern University Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland. carmen.pfortmueller@insel.ch.
University Hospital of Bern · CHUniversity of Bern · CHHirslanden Klinik Im Park · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuick sequential organ failure assessement (qSOFA) has been validated for patients with presumed sepsis and the general emergency department (ED) population. However, it has not been validated in specific subgroups of ED patients with a high mortality. We aimed to investigate the prognostic performance of qSOFA with respect to in-hospital mortality, intensive care unit (ICU) admission, and length of hospitalisation in patients with decompensated liver cirrhosis. Furthermore, we compared qSOFA to systemic inflammatory response syndrome (SIRS), model of end stage liver disease score (MELD), and Child-Pugh criteria and evaluated whether addition of sodium (Na

methodsThis observational study included patients admitted with the diagnosis of decompensated liver cirrhosis. All patients with a complete set of vital parameters were included in this study.

resultsA total of 186 patients were included. A positive qSOFA score was not associated with in-hospital mortality, ICU admission, or length of hospitalisation (all p > 0.15). MELD scores reliably predicted need for ICU admission and in-hospital mortality (both p < 0.01), but not the length of hospitalisation. qSOFA-Na+ only moderately increased the diagnostic performance of qSOFA with regard to need for ICU admission (AUC

conclusionqSOFA does not predict in-hospital mortality, ICU admission or length of hospitalisation in patients with decompensated liver cirrhosis. Extension of qSOFA with a disease-specific component, the qSOFA-Na+, moderately increased the diagnostic ability of qSOFA.

Indexed as

Hospital MortalityLiver CirrhosisOrgan Dysfunction ScoresSepsisHumansPrognosisRetrospective StudiesSystemic Inflammatory Response SyndromeCritical illnessElectrolyte disorderEmergency admissionsMortality predictionQSOFA extendedSodium

Identifiers

PMID30132026
OpenAlexW2888769744

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.