Evidence map›Paper›PMID 30131804›Full record

ArticleFrontiers in immunology2018

Toll-Interleukin 1 Receptor Domain-Containing Adaptor Protein 180L Single-Nucleotide Polymorphism Is Associated With Susceptibility to Recurrent Pneumococcal Lower Respiratory Tract Infections in Children.

Johan N Siebert, Lutz Hamann, Charlotte M Verolet, Cécile Gameiro, Stéphane Grillet, Claire-Anne Siegrist, Klara M Posfay-Barbe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Johan N SiebertDepartment of Pediatric Emergency Medicine, Geneva Children's Hospital, Geneva University Hospitals, Geneva, Switzerland.
Lutz HamannInstitute of Medical Microbiology and Hygiene, Charité-University Medical Center Berlin, Berlin, Germany.
Charlotte M VeroletDepartment of Pediatrics, Geneva Children's Hospital, Geneva University Hospitals, Geneva, Switzerland.
Cécile GameiroFlow Cytometry Core Facility, Geneva University Medical Center, Geneva, Switzerland.
Stéphane GrilletDepartment of Pathology-Immunology and Pediatrics, Center for Vaccinology and Neonatal Immunology, Geneva Medical Center, Geneva, Switzerland.
Claire-Anne SiegristDepartment of Pathology-Immunology and Pediatrics, Center for Vaccinology and Neonatal Immunology, Geneva Medical Center, Geneva, Switzerland.
Klara M Posfay-BarbeDepartment of Pediatrics, Geneva Children's Hospital, Geneva University Hospitals, Geneva, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lower respiratory tract infections (LRTI) are often caused by

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideStreptococcus pneumoniaeAdultAge FactorsAllelesBiomarkersCase-Control StudiesChildChild, PreschoolFemaleGene ExpressionGenetic Association StudiesGenotypeHumansImmunophenotypingBiomarkersMembrane GlycoproteinsReceptors, Interleukin-1Receptors, Pattern RecognitionTIRAP protein, humanToll-Like Receptorschildimmunityinnatepneumoniapolymorphismsingle nucleotideStreptococcus pneumoniaetoll-like receptors

Identifiers

PMID30131804
PMCPMC6090034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.