Evidence map›Paper›PMID 30131678›Full record

ArticleFrontiers in neural circuits2018

Serotonergic Regulation of Corticoamygdalar Neurons in the Mouse Prelimbic Cortex.

Daniel Avesar, Emily K Stephens, Allan T Gulledge

Abstract read
In one paragraph

Article in Frontiers in neural circuits, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Common and contrasting effects of 5-HTergic signaling in pyramidal cells and SOM interneurons of the mouse cortex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025
    Article
  3. Article
  4. Emotional Memory Processing during REM Sleep with Implications for Post-Traumatic Stress Disorder.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel AvesarDepartment of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, United States.
Emily K StephensDepartment of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, United States.
Allan T GulledgeDepartment of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, United States.

Funding

Neuromodulation of cortical circuits in health and diseaseR01MH099054 · NIMH · DARTMOUTH COLLEGE · PI GULLEDGE, ALLAN T · 2013 to 2017
$2.0M
NIMH NIH HHS R01 MH099054
6 · The paper itself

Abstract

Neuromodulatory transmitters, such as serotonin (5-HT), selectively regulate the excitability of subpopulations of cortical projection neurons to gate cortical output to specific target regions. For instance, in the mouse prelimbic cortex, 5-HT selectively excites commissurally projecting (COM) intratelencephalic neurons via activation of 5-HT

Indexed as

AmygdalaAnimalsElectrophysiological PhenomenaFemaleMaleMiceMice, Inbred C57BLPrefrontal CortexPyramidal CellsReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT2ASerotoninReceptor, Serotonin, 5-HT1AReceptor, Serotonin, 5-HT2ASerotonin5-HT1A receptor5-HT2A receptorcorticoamygdalar projectionprefrontal cortexpyramidal neuronserotonin

Identifiers

PMID30131678
PMCPMC6090182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.