ArticleBritish journal of cancer2018
Childhood cancer research in oxford III: The work of CCRG on ionising radiation.
Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Using primary teeth and archived dried spots for exposomic studies in children: Exploring new paths in the environmental epidemiology of pediatric cancer.BioEssays : news and reviews in molecular, cellular and developmental biology · 2021Review
- Article
- Cancer Progress and Priorities: Childhood Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020Article
- Case-control study of paternal occupational exposures and childhood lymphoma in Great Britain, 1962-2010.British journal of cancer · 2019Article
- Childhood cancer research in Oxford II: The Childhood Cancer Research Group.British journal of cancer · 2018Article
- Childhood cancer research in Oxford I: the Oxford Survey of Childhood Cancers.British journal of cancer · 2018Article
- Childhood cancer in the UK: achievements and legacy of six decades of research in Oxford.British journal of cancer · 2018Article
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8 authors.
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Abstract
backgroundHigh doses of ionising radiation are a known cause of childhood cancer and great public and professional interest attaches to possible links between childhood cancer and lower doses, particularly of man-made radiation. This paper describes work done by the Childhood Cancer Research Group (CCRG) on this topic
methodsMost UK investigations have made use of the National Registry of Childhood Tumours and associated controls. Epidemiological investigations have included national incidence and mortality analyses, geographical investigations, record linkage and case-control studies. Dosimetric studies use biokinetic and dosimetric modelling.
resultsThis paper reviews the work of the CCRG on the association between exposure to ionising radiation and childhood cancer, 1975-2014.
conclusionThe work of CCRG has been influential in developing understanding of the causes of 'clusters' of childhood cancer and the risks arising from exposure to ionising radiation both natural and man-made. Some clusters around nuclear installations have certainly been observed, but ionising radiation does not seem to be a plausible cause. The group's work has also been instrumental in discounting the hypothesis that paternal preconception irradiation was a cause of childhood cancers and has demonstrated an increased leukaemia risk for children exposed to higher levels of natural gamma-ray radiation.
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