Evidence map›Paper›PMID 30131457›Full record

ReviewNutrients2018

Acute and Chronic Effects of Exercise on Appetite, Energy Intake, and Appetite-Related Hormones: The Modulating Effect of Adiposity, Sex, and Habitual Physical Activity.

James Dorling, David R Broom, Stephen F Burns, David J Clayton, Kevin Deighton, Lewis J James, James A King, Masashi Miyashita, Alice E Thackray, Rachel L Batterham and 1 more

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04616235 (Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade - a Randomized Controlled Trial), which is not on this map. Cited by 106 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 7 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04616235 nacompletednot on this mapstarted 2021, after this paper: background citation

Acute Exercise and NK Cell Regulation in Tissue and Circulation After IL-6R Blockade - a Randomized Controlled Trial

TypeinterventionalSponsorRigshospitalet, DenmarkRan2021 to 2021Enrolled30ConditionsInterleukin-6 Inhibition, Physical Stress, Appetitive BehaviorArmsTocilizumab Injectable Product, Saline 0.9% 100 ml NaCl 0.9% will be infused over 1 hour
3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 7 syntheses or guidelines pooled it, 217 citations in OpenAlex.

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  13. Effects of a Physical Activity mHealth Intervention (Fit2Thrive) on WCRF/AICR Cancer Prevention Recommendations among Breast Cancer Survivors: A Secondary Data Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

James DorlingNational Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire LE11 3TU, UK. J.L.Dorling@lboro.ac.uk.
David R BroomAcademy of Sport and Physical Activity, Faculty of Health and Wellbeing, Sheffield Hallam University, Sheffield S10 2BP, UK. D.R.Broom@shu.ac.uk.ORCID 0000-0002-0305-937X
Stephen F BurnsPhysical Education and Sports Science Academic Group, Nanyang Technological University, Singapore 637616, Singapore. Stephen.Burns@nie.edu.sg.ORCID 0000-0001-7192-4735
David J ClaytonSchool of Science and Technology, Nottingham Trent University, Nottingham NG11 8NF, UK. David.Clayton@ntu.ac.uk.ORCID 0000-0001-5481-0891
Kevin DeightonInstitute for Sport, Physical Activity and Leisure, Leeds Beckett University, Leeds LS6 3QS, UK. K.Deighton@leedsbeckett.ac.uk.ORCID 0000-0001-7994-2137
Lewis J JamesNational Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire LE11 3TU, UK. L.James@lboro.ac.uk.
James A KingNational Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire LE11 3TU, UK. J.A.King@lboro.ac.uk.
Masashi MiyashitaFaculty of Sport Sciences, Waseda University, Saitama 169-8050, Japan. M.Miyashita@waseda.jp.
Alice E ThackrayNational Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire LE11 3TU, UK. A.E.Thackray@lboro.ac.uk.ORCID 0000-0002-7800-3207
Rachel L BatterhamCentre for Obesity Research, University College London, London WC1E 6BT, UK. R.Batterham@ucl.ac.uk.
David J StenselNational Centre for Sport and Exercise Medicine, School of Sport, Exercise and Health Sciences, Loughborough University, Leicestershire LE11 3TU, UK. D.J.Stensel@lboro.ac.uk.
Loughborough University · GBLeeds Beckett University · GBNanyang Technological University · SGNottingham Trent University · GBRoyal London Hospital · GBSheffield Hallam University · GBWaseda University · JP

Funding

Department of Health RP-2015-06-005
6 · The paper itself

Abstract

Exercise facilitates weight control, partly through effects on appetite regulation. Single bouts of exercise induce a short-term energy deficit without stimulating compensatory effects on appetite, whilst limited evidence suggests that exercise training may modify subjective and homeostatic mediators of appetite in directions associated with enhanced meal-induced satiety. However, a large variability in responses exists between individuals. This article reviews the evidence relating to how adiposity, sex, and habitual physical activity modulate exercise-induced appetite, energy intake, and appetite-related hormone responses. The balance of evidence suggests that adiposity and sex do not modify appetite or energy intake responses to acute or chronic exercise interventions, but individuals with higher habitual physical activity levels may better adjust energy intake in response to energy balance perturbations. The effect of these individual characteristics and behaviours on appetite-related hormone responses to exercise remains equivocal. These findings support the continued promotion of exercise as a strategy for inducing short-term energy deficits irrespective of adiposity and sex, as well as the ability of exercise to positively influence energy balance over the longer term. Future well-controlled studies are required to further ascertain the potential mediators of appetite responses to exercise.

Indexed as

AdiposityAppetiteEnergy IntakeExerciseAppetite RegulationEnergy MetabolismFemaleGhrelinHomeostasisHumansMaleMealsSatiationGhrelinappetiteappetite-related hormonesenergy balanceenergy compensationenergy intakeexercisephysical activityweight control

Identifiers

PMID30131457
PMCPMC6164815
OpenAlexW2884106931

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.