Evidence map›Paper›PMID 30131339›Full record

ArticleThe Journal of biological chemistry2018

CARM1 suppresses

Tharindumala Abeywardana, Myungeun Oh, Lei Jiang, Ying Yang, Mei Kong, Jikui Song, Yanzhong Yang

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Promising Role of PKM2 in the Diagnosis and Prognosis of Ovarian Cancer.Anti-cancer agents in medicinal chemistry · 2026
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. The emerging role of CARM1 in cancer.Cellular oncology (Dordrecht, Netherlands) · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Protein arginine methylation in transcription and epigenetic regulation.Frontiers in epigenetics and epigenomics · 2023
    Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Tharindumala AbeywardanaFrom the Departments of Cancer Genetics and Epigenetics and.
Myungeun OhMolecular and Cellular Endocrinology, Beckman Research Institute, City of Hope Cancer Center, Duarte, California 91010.
Lei JiangMolecular and Cellular Endocrinology, Beckman Research Institute, City of Hope Cancer Center, Duarte, California 91010.
Ying Yangthe Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, and.
Mei Kongthe Department of Molecular Biology and Biochemistry, University of California, Irvine, California 92697, and.
Jikui Songthe Department of Biochemistry, University of California, Riverside, California 92521.
Yanzhong YangFrom the Departments of Cancer Genetics and Epigenetics and yyang@coh.org.
Beckman Research InstituteCity of Hope · USUniversity of California, Irvine · USUniversity of California, Riverside · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
Mechanistic Insights into Mammalian DNA MethylationR35GM119721 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Jikui Song · 2016 to 2026
$5.3M
Cancer Cell Adaption to Glutamine DeprivationR01CA183989 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI KONG, MEI · 2014 to 2019
$1.7M
NCI NIH HHS P30 CA033572NCI NIH HHS R01 CA183989NIGMS NIH HHS R35 GM119721
6 · The paper itself

Abstract

Glucose is a critical nutrient for cell proliferation. However, the molecular pathways that regulate glucose metabolism are still elusive. We discovered that co-activator-associated arginine methyltransferase 1 (CARM1) suppresses glucose metabolism toward serine biosynthesis. By tracing the

Indexed as

AnimalsArginineCarrier ProteinsCell Line, TumorCell ProliferationCrystallography, X-RayFibroblastsGlucoseGlycolysisHumansMembrane ProteinsMethylationMiceMice, KnockoutProtein-Arginine N-MethyltransferasesProtein IsoformsArginineCarrier Proteinscoactivator-associated arginine methyltransferase 1GlucoseMembrane ProteinsPkm protein, mouseProtein-Arginine N-MethyltransferasesProtein IsoformsPyruvate KinaseSerineThyroid Hormone-Binding ProteinsThyroid HormonesCARM1metabolic regulationproliferationprotein methylationpyruvate kinaseserine

Identifiers

PMID30131339
PMCPMC6166735
OpenAlexW2888148995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.