ArticlePsychological medicine2019
Can we predict the direction of sudden shifts in symptoms? Transdiagnostic implications from a complex systems perspective on psychopathology.
Article in Psychological medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed.
- Proximal Effects of a Transdiagnostic, Ecological Momentary Intervention for Enhancing Resilience in Help-Seeking Young People (EMIcompass): Findings From a Secondary Analysis of an Exploratory Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Mapping the dynamics of idiographic network models to the network theory of psychopathology.Behavior research methods · 2026Article
- Computational modeling of the temporal influences between cues, craving and use in addiction: a dynamical system analysis based on ecological momentary assessment data.Translational psychiatry · 2025Article
- Problem-sustaining patterns: redesigning the concept of mental disorder.Frontiers in psychiatry · 2025Article
- Network analysis: An overview for mental health research.International journal of methods in psychiatric research · 2024Review
- Ruminative Variability Predicts Increases in Depression and Social Anxiety.Cognitive therapy and research · 2024Article
- A complex systems perspective on chronic aggression and self-injury: case study of a woman with mild intellectual disability and borderline personality disorder.BMC psychiatry · 2024Article
- Detecting Prolonged Stress in Real Life Using Wearable Biosensors and Ecological Momentary Assessments: Naturalistic Experimental Study.Journal of medical Internet research · 2023Article
- Pattern breaking: a complex systems approach to psychedelic medicine.Neuroscience of consciousness · 2023Article
- An Experience Sampling Measure of the Key Features of Rumination.Clinical neuropsychiatry · 2022Article
- Anticipating manic and depressive transitions in patients with bipolar disorder using early warning signals.International journal of bipolar disorders · 2022Article
- Anticipating the direction of symptom progression using critical slowing down: a proof-of-concept study.BMC psychiatry · 2022Article
- Grievance-fueled violence can be better understood using an enactive approach.Frontiers in psychology · 2022Review
- Permutation Entropy as a Universal Disorder Criterion: How Disorders at Different Scale Levels Are Manifestations of the Same Underlying Principle.Entropy (Basel, Switzerland) · 2021Article
- On the transience or stability of subthreshold psychopathology.Scientific reports · 2021Article
- Modeling the onset of a depressive episode: A self-regulation perspective.Current opinion in psychology · 2021Review
- A novel, complex systems approach to modelling risk of psychological distress in young adolescents.Scientific reports · 2021Article
- Early warning signals in psychopathology: what do they tell?BMC medicine · 2020Article
- A complex systems approach to the study of change in psychotherapy.BMC medicine · 2020Article
- Measuring psychopathology as it unfolds in daily life: addressing key assumptions of intensive longitudinal methods in the TRAILS TRANS-ID study.BMC psychiatry · 2020Article
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4 authors.
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Abstract
Recently, there has been renewed interest in the application of assumptions from complex systems theory in the field of psychopathology. One assumption, with high clinical relevance, is that sudden transitions in symptoms may be anticipated by rising instability in the system, which can be detected with early warning signals (EWS). Empirical studies support the idea that this principle also applies to the field of psychopathology. The current manuscript discusses whether assumptions from complex systems theory can additionally be informative with respect to the specific symptom dimension in which such a transition will occur (e.g. whether a transition towards anxious, depressive or manic symptoms is most likely). From a complex systems perspective, both EWS measured in single symptom dynamics and network symptom dynamics at large are hypothesized to provide clues regarding the direction of the transition. Challenging research designs are needed to provide empirical validation of these hypotheses. These designs should be able to follow sudden transitions 'live' using frequent observations of symptoms within individuals and apply a transdiagnostic approach to psychopathology. If the assumptions proposed are supported by empirical studies then this will signify a large improvement in the possibility for personalized estimations of the course of psychiatric symptoms. Such information can be extremely useful for early intervention strategies aimed at preventing specific psychiatric problems.
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