ArticleBMC musculoskeletal disorders2018
Individuals with mild-to-moderate hip osteoarthritis have lower limb muscle strength and volume deficits.
Article in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Effectiveness of Exercise in Patients with Overweight or Obesity Suffering from Knee Osteoarthritis: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Pooled it
- Effects of a targeted resistance intervention compared to a sham intervention on gluteal muscle hypertrophy, fatty infiltration and strength in people with hip osteoarthritis: analysis of secondary outcomes from a randomised clinical trial.BMC musculoskeletal disorders · 2022Trial
- Trial
- Identification of Gait Abnormalities in Patients with Hip Osteoarthritis Using a Monocular Vision 3D Motion Capture System.Bioengineering (Basel, Switzerland) · 2026Article
- People With Marfan Syndrome Utilize an Ankle Dominant Strategy to Perform the Sit-to-Stand Task.Journal of applied biomechanics · 2026Article
- Effect of hip bracing on stair walking biomechanics and pain in patients with mild-to-moderate hip osteoarthritis: an intervention study.BMC musculoskeletal disorders · 2026Article
- Neuromuscular mechanisms for the fast decline in rate of force development with muscle disuse - a narrative review.The Journal of physiology · 2026Review
- Electroacupuncture Combined with Diclofenac Emulgel for Post-Traumatic Ankle Osteoarthritis: A Randomized Controlled Trial Protocol.Journal of pain research · 2026Article
- Network analysis reveals that total hip arthroplasty restores shared segmental motion before segmental differentiation.Frontiers in network physiology · 2026Article
- The Notch signaling pathway in regulating bone and cartilage homeostasis: novel insights into the pathogenesis and therapeutics of osteoarthritis.Cell communication and signaling : CCS · 2025Review
- Determining the effect of femoral anteversion and hip alignment parameters on lower limb and knee alignment post-total hip arthroplasty.Scientific reports · 2025Article
- Review of Methods for Evaluating Changes in the Tension and Properties of the Gluteus Medius Muscle (GMED) and the Tensor Fascia Latae (TFL) as a Result of Hip Osteoarthritis (HOA) and After Total Hip Arthroplasty (THA)-Could MyotonPRO Assessment Be the New Standard?Journal of clinical medicine · 2025Review
- Volume and quality of the gluteal muscles are associated with early physical function after total hip arthroplasty.International journal of computer assisted radiology and surgery · 2025Article
- Intra- and Inter-Rater Reliability of Ultrasound Imaging to Measure Tensor Fasciae Latae Muscle Size.Journal of clinical medicine · 2025Article
- Individual joint contributions to forward propulsion during treadmill walking in women with hip osteoarthritis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Diagnostic value of multiple projection angle X-ray and CT 3D reconstruction for long-term unreduced posterior hip dislocation.Frontiers in surgery · 2025Article
- Predictive and classification capabilities of the timed up and go as a physical performance measure in hip osteoarthritis: a retrospective study of 606 patients.Archives of orthopaedic and trauma surgery · 2024Article
- Mobility Requirements and Joint Loading during Straight Walking and 90° Turns in Healthy Older People and Those with Hip Osteoarthritis.Journal of clinical medicine · 2024Article
- Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIndividuals with advanced hip osteoarthritis (OA) exhibit generalized muscle weakness of the affected limb and so clinical practice guidelines recommend strength training for the management of hip OA. However, the extent and pattern of muscle weakness, including any between-limb asymmetries, in early stages of the disease are unclear. This study compared hip and knee muscle strength and volumes between individuals with mild-to-moderate symptomatic and radiographic hip OA and a healthy control group.
methodsNineteen individuals with mild-to-moderate symptomatic and radiographic hip OA (n = 12 unilateral; n = 7 bilateral) and 23 age-matched, healthy controls without radiographic hip OA or hip pain participated. Isometric strength of the hip and knee flexors and extensors, and hip abductors and adductors were measured. Hip and thigh muscle volumes were measured from lower limb magnetic resonance images. A full-factorial, two-way General Linear Model was used to assess differences between groups and between limbs.
resultsParticipants in the hip OA group demonstrated significantly lower knee flexor, knee extensor, hip flexor, hip extensor and hip abductor strength compared to controls and had significantly lower volume of the adductor, hamstring and quadriceps groups, and gluteus maximus and gluteus minimus muscles, but not tensor fasciae latae or gluteus medius muscles. There were no between-limb strength differences or volume differences within either group.
conclusionsAtrophic, bilateral hip and knee muscle weakness is a feature of individuals with mild-to-moderate hip OA. Early interventions to target muscle weakness and prevent the development of strength asymmetries that are characteristic of advanced hip OA appear warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.