ArticleKorean journal of pediatrics2018
Increased procalcitonin level is a risk factor for prolonged fever in children with Mycoplasma pneumonia.
Article in Korean journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Novel inflammatory biomarkers and disease severity in hospitalized children withTranslational pediatrics · 2026Article
- Diagnostic value of cytokine detection in children with Mycoplasma pneumoniae pneumonia complicated by bacterial or viral co-infections.BMC pediatrics · 2026Article
- Role of Serum Inflammatory Biomarkers in Risk Stratification of Hospitalized Children with Macrolide-Non-ResponsiveChildren (Basel, Switzerland) · 2026Article
- Influence of Mycoplasma Resistance Genes on Pediatric Mycoplasma Pneumonia Treatment and Determinants for Second-line Antimicrobial Adjustment.Combinatorial chemistry & high throughput screening · 2026Article
- Clinical features of MPP with or without viruses among hospitalized children in 2023, Wenzhou, Zhejiang, China.Italian journal of pediatrics · 2025Article
- A comparison of diagnostic and therapeutic approaches for Mycoplasma pneumoniae pneumonia in children and adults, during the post-COVID-19 pandemic era.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025Article
- Epidemiological association of the COVID-19 pandemic onBMJ open · 2025Article
- Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease.Annals of intensive care · 2025Review
- Construction and verification of a risk factor prediction model for neonatal severe pneumonia.Frontiers in medicine · 2025Article
- Exploring high-risk factors for the prediction of severe mycoplasma pneumonia in children.Translational pediatrics · 2024Article
- Correlation of DNA load, genotyping, and clinical phenotype ofFrontiers in pediatrics · 2024Article
- Clinical, Laboratory, and Radiographic Features Can Help PredictMicroorganisms · 2023Article
- Effect of sea buckthorn extract on production performance, serum biochemical indexes, egg quality, and cholesterol deposition of laying ducks.Frontiers in veterinary science · 2023Article
- Prediction of Bronchopneumonia Inpatients' Total Hospitalization Expenses Based on BP Neural Network and Support Vector Machine Models.Computational and mathematical methods in medicine · 2022Article
- Highly Expressed lncRNA GAS5 in the Serum of Children withContrast media & molecular imaging · 2022Article
- Clinical Significance of Pleural Effusion inPathogens (Basel, Switzerland) · 2021Article
- Early Confirmation ofDiagnostics (Basel, Switzerland) · 2021Article
- [Clinical features of children withZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021Article
- Improved Diagnostics Help to Identify Clinical Features and Biomarkers That Predict Mycoplasma pneumoniae Community-acquired Pneumonia in Children.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMacrolide-resistant Mycoplasma pneumoniae pneumonia (MPP) is characterized by prolonged fever and radiological progression despite macrolide treatment. Few studies have examined serum procalcitonin (PCT) level in children with MPP. We aimed to investigate the association of acute inflammation markers including PCT with clinical parameters in children with MPP.
methodsA total of 147 children were recruited. The diagnosis of MPP relied on serial measurement of IgM antibody against mycoplasma and/or polymerase chain reaction. We evaluated the relationships between C-reactive protein (CRP), PCT, and lactate dehydrogenase (LDH) levels and white blood cell (WBC) counts, and clinical severity of the disease. We used multivariate logistic regression analysis to estimate the odds ratio for prolonged fever (>3 days after admission) and hospital stay (> 6 days), comparing quintiles 2-5 of the PCT levels with the lowest quintile.
resultsThe serum PCT and CRP levels were higher in children with fever and hospital stay than in those with fever lasting ≤ 3 days after admission and hospital stay ≤ 6 days. CRP level was higher in segmental/lobar pneumonia than in bronchopneumonia. The LDH level and WBC counts were higher in children with fever lasting for >3 days before compared to those with fever lasting for ≤ 3 days. The highest quintile of PCT levels was associated with a significantly higher risk of prolonged fever and/or hospital stay than the lowest quintile.
conclusionSerum PCT and CRP levels on admission day were associated with persistent fever and longer hospitalization in children with MPP.
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