SynthesisJournal of the National Medical Association2019
Racial Disparities in Arterial Stiffness Between Healthy Whites and African Americans in the United States: A Meta-analysis.
Synthesis in Journal of the National Medical Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 12 citations in OpenAlex.
- Disparities in Blood Pressure Measurement.Current hypertension reports · 2026Review
- Mortality trends and disparities associated with aortic aneurysm and aortic dissection in the United States from 1999 to 2023: a CDC WONDER database analysis.BMC cardiovascular disorders · 2026Article
- Evidence of racial differences in peripheral blood pressure, central haemodynamics and arterial stiffness between young Black and White women.Experimental physiology · 2026Article
- Associations between potassium, arterial stiffness, and risk of cardiovascular disease in the Jackson Heart Study: Potassium, arterial stiffness, and CVD risk.American journal of preventive cardiology · 2025Article
- Different Level of Carotid-Femoral Pulse Wave Velocity and Related Factors in Different Nationality Group in China.Vascular health and risk management · 2025Article
- Discrimination, religious affiliation, and arterial stiffness in African American women and men.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- Central Hemodynamics in African American Women: Examining the Role of Superwoman Schema Endorsement.Journal of the American Heart Association · 2024Article
- Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.HGG advances · 2021Article
- MicroRNA-1253 Regulation of WASF2 (WAVE2) and its Relevance to Racial Health Disparities.Genes · 2020Article
- Backward in Coming Forward.American journal of hypertension · 2019Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAfrican Americans (AAs) present with cardiovascular disease (CVD) risk factors at younger ages than whites. Consequently, CVD and stroke occur at a higher incidence and at earlier decades in life in AA populations. Arterial stiffness is a predictor of CVD outcomes and partially explains the CVD risk experienced by racial minorities. We evaluated the differences in arterial stiffness observed in AAs and whites through a systematic review and meta-analysis.
methodsWe searched PubMed and SCOPUS for comparative studies published March 1995 to November 29, 2017 comparing arterial stiffness assessments (pulse wave velocity, augmentation index, and central blood pressure) between AAs and whites. Two independent reviewers examined 195 titles/abstracts, 85 full text articles and 11 articles were included in the meta-analysis using random effects modeling approaches. MAIN
resultsA total of 5060 white and 3225 AAs were included across 11 relevant studies. Carotid-femoral pulse wave velocity (cfPWV) measures were statistically different between AAs and whites (mean difference = -0.44, 95% confidence interval [CI]: -[-0.67, -0.21], p = 0.0002). Aortic femoral pulse wave velocity was significantly different between AAs and whites (mean difference = -0.21, [95% CI] -0.35, -0.07, p = 0.003) regardless of sex. Augmentation index (AIx) and Augmentation index at a 75 beats per minutes heart rate (AIx @75) was also significantly different between AA and whites (mean difference = -4.36 [95% CI] = -6.59, -2,12, p = 0.0001 and -6.26, [95% CI] = -9.19, -3.33, p < 0.0001, respectively).
conclusionsRacial disparities in arterial stiffness persist among African American racial groups in the United States. The lack of homogeneity in studies capturing racial disparities in cfPWV suggest that additional studies are needed to understand the magnitude of racial differences in African Americans and whites that might be clinically relevant.
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