Evidence map›Paper›PMID 30129226›Full record

ReviewBritish journal of pharmacology2020

Brain histamine modulates recognition memory: possible implications in major cognitive disorders.

Gustavo Provensi, Alessia Costa, Ivan Izquierdo, Patrizio Blandina, Maria Beatrice Passani

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. A Closer Look at Histamine inInternational journal of molecular sciences · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Drug Repurposing to Inhibit HistamineMolecules (Basel, Switzerland) · 2023
    Article
  16. Repurposing Histaminergic Drugs in Multiple Sclerosis.International journal of molecular sciences · 2022
    Article
  17. New Chemical Biology Tools for the Histamine Receptor Family.Current topics in behavioral neurosciences · 2022
    Article
  18. Different Peas in the Same Pod: The Histaminergic Neuronal Heterogeneity.Current topics in behavioral neurosciences · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Gustavo ProvensiDepartment of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy.ORCID 0000-0002-6182-6848
Alessia CostaDepartment of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.
Ivan IzquierdoMemory Center, Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil.
Patrizio BlandinaDepartment of Neuroscience, Psychology, Drug Research and Child Health, Section of Pharmacology and Toxicology, University of Florence, Florence, Italy.
Maria Beatrice PassaniDepartment of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence, Italy.ORCID 0000-0002-7729-9069
University of Florence · ITInstituto do Cérebro · BR

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 201511/2014-2Ministero della Salute, Bando Ricerca Finalizzata e Giovani Ricercatori GR-201102346829Universitá degli Studi di Firenze DR 175372-1210
6 · The paper itself

Abstract

Several behavioural tests have been developed to study and measure emotionally charged or emotionally neutral memories and how these may be affected by pharmacological, dietary or environmental manipulations. In this review, we describe the experimental paradigms used in preclinical studies to unravel the brain circuits involved in the recognition and memorization of environmentally salient stimuli devoid of strong emotional value. In particular, we focus on the modulatory role of the brain histaminergic system in the elaboration of recognition memory that is based on the judgement of the prior occurrence of an event, and it is believed to be a critical component of human declarative memory. The review also addresses questions that may help improve the treatment of impaired declarative memory described in several affective and neuropsychiatric disorders such as ADHD, Alzheimer's disease and major neurocognitive disorder. LINKED ARTICLES: This article is part of a themed section on New Uses for 21st Century. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.3/issuetoc.

Indexed as

Cognition DisordersHistamineBrainCognitionHumansMemoryHistamine

Identifiers

PMID30129226
PMCPMC7012952
OpenAlexW2888535090

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.