Evidence map›Paper›PMID 30129188›Full record

ArticleJournal of clinical laboratory analysis2019

Neutrophil-to-C3 ratio and neutrophil-to-lymphocyte ratio were associated with disease activity in patients with systemic lupus erythematosus.

Jianlin Yu, Tingting Zeng, Yang Wu, Yongjian Tian, Liming Tan, Xinwang Duan, Qiong Wu, Hua Li, Le Yu

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04110184 (Haematological Indices in Systemic Lupus Erythematosus and Their Association With Disease Activity), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04110184 unknown statusnot on this map

Haematological Indices in Systemic Lupus Erythematosus and Their Association With Disease Activity

TypeobservationalSponsorAssiut UniversityRan2019 to 2023Enrolled84ConditionsRheumatic Diseases, Systemic Lupus ErythematosusArmsSystemic lupus erythematosus disease activity index (SLEDAI)
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  14. C-reactive protein/albumin ratio as an indicator of disease activity in Behçet's disease and human leukocyte antigen-B27-associated uveitis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  15. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jianlin YuDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.ORCID http://orcid.org/0000-0002-1002-3818
Tingting ZengDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yang WuDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Yongjian TianDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Liming TanDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Xinwang DuanDepartment of Rheumatology of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Qiong WuDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Hua LiDepartment of Clinical Laboratory of the Second Affiliated Hospital, Nanchang University, Nanchang, China.
Le YuDepartment of Rheumatology of the Second Affiliated Hospital, Nanchang University, Nanchang, China.

Funding

Jiangxi Natural Science Foundation Grants Project 2017BAB205076Jiangxi provincial education department science and technology research project 160157The National Natural Science Foundation of China 81760382
6 · The paper itself

Abstract

backgroundSystemic lupus erythematosus is prone to recurrent attacks, and its treatment is related to disease activities. It is important to accurately assess the patient's disease activity. So, the purpose of this study was to investigate the relation between neutrophil-to-C

methodsThis was a retrospective study. One hundred and ninety-four patients with SLE and 71 healthy controls were included in this study. We divided the patients into two groups according to the SLE disease activity (SLEDAI). Group 1 included patients with a score of >9 (patients with severe disease activity), and Group 2 included patients with a score of 9 and lower (patients with mild disease activity). Correlations between NC

resultsNC

conclusionNC

Indexed as

Lupus Erythematosus, SystemicAdultComplement C3FemaleHumansMaleMiddle AgedNeutrophilsC3 protein, humanComplement C3disease activityneutrophil-to-C3 rationeutrophil-to-lymphocyte ratiosystemic lupus erythematosus

Identifiers

PMID30129188
PMCPMC6430331

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.