Trial reportEuropean journal of applied physiology2018
L-Menthol mouth rinse or ice slurry ingestion during the latter stages of exercise in the heat provide a novel stimulus to enhance performance despite elevation in mean body temperature.
Trial report in European journal of applied physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Effects of different menthol administration routes on endurance performance and physiological responses in the heat: a network meta-analysis.Frontiers in nutrition · 2026Pooled it
- Effects of carbohydrate, caffeine and menthol mouth rinses on exercise performance and ratings of perceived exertion: a systematic review and network meta-analysis.Frontiers in nutrition · 2026Pooled it
- Pooled it
- How Cool is That? The Effects of Menthol Mouth Rinsing on Exercise Capacity and Performance: A Systematic Review and Meta-analysis.Sports medicine - open · 2024Pooled it
- Performance Benefits of Pre- and Per-cooling on Self-paced Versus Constant Workload Exercise: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Effects of internal cooling on physical performance, physiological and perceptional parameters when exercising in the heat: A systematic review with meta-analyses.Frontiers in physiology · 2023Pooled it
- Performance effects of internal pre- and per-cooling across different exercise and environmental conditions: A systematic review.Frontiers in nutrition · 2022Pooled it
- Menthol can be safely applied to improve thermal perception during physical exercise: a meta-analysis of randomized controlled trials.Scientific reports · 2020Pooled it
- Effects of carbohydrate-electrolyte solutions with and without L-menthol on hydration and performance recovery following simulated firefighting exercise.Journal of the International Society of Sports Nutrition · 2026Trial
- Acute Effects of Caffeine and Taurine Co-Ingestion on Time to Exhaustion and Thermoregulatory Responses to Cycling in the Heat.European journal of sport science · 2025Trial
- A Menthol-Enhanced "Cooling" Energy Gel Does Not Influence Laboratory Time Trial Performance in Trained Runners.Nutrients · 2023Trial
- Menthol Mouth Rinsing Maintains Relative Power Production during Three-Minute Maximal Cycling Performance in the Heat Compared to Cold Water and Placebo Rinsing.International journal of environmental research and public health · 2022Trial
- Athlete perceptions of flavored, menthol-enhanced energy gels ingested prior to endurance exercise in the heat.Journal of the International Society of Sports Nutrition · 2022Trial
- Trial
- Nutritional Strategies to Support Performance Maintenance and Recovery in Football Under Hot Environmental Conditions: A Narrative Review.Nutrients · 2026Review
- Determination of the optimal dose and dosing strategy for effective L-menthol oral rinsing during exercise in hot environments.European journal of applied physiology · 2025Article
- The Effect of Menthol Mouth Rinsing and Fluid Temperature on Male Cycling Performance in Thermoneutral Conditions.Nutrients · 2024Article
- The effect of menthol rinsing before intermittent exercise on physiological, physical, and thermo-behavioral responses of male football referees in hot and humid environment.Frontiers in sports and active living · 2024Article
- Assessing the usability of aromatic mouthwashes in alleviating physiological stress responses.Frontiers in oral health · 2024Article
- Menthol mouth rinsing and performance in elite football referees in the heat: A study protocol for a randomized crossover trial.Contemporary clinical trials communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study investigated the effects of L-menthol mouth rinse and ice slurry ingestion on time to exhaustion, when administered at the latter stages (~ 85%) of baseline exercise duration in the heat (35 °C).
methodTen male participants performed four time to exhaustion (TTE) trials on a cycle ergometer at 70% W
resultsFrom the point of administration at 85% of baseline TTE, exercise time was extended by 1% (placebo, 15 s), 6% (L-menthol, 82 s) and 7% (ice, 108 s), relative to baseline performance (P = 0.036), with no difference between L-menthol and ice (P > 0.05). Core temperature, skin temperature, and heart rate increased with time but did not differ between conditions (P > 0.05). Thermal sensation did not differ significantly but demonstrated a large effect size (P = 0.080; [Formula: see text] = 0.260).
conclusionThese results indicate that both thermally cooling and non-thermally cooling oral stimuli have an equal and immediate behavioral, rather than physiological, influence on exhaustive exercise in the heat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.